Mutations in a conserved loop in the PSST subunit of respiratory complex I affect ubiquinone binding and dynamics

Yoga, EG; Haapanen, O; Wittig, I; Siegmund, K; Sharrna, V; Zickermann, V

Sharrna, V (reprint author), Univ Helsinki, Dept Phys, Gustaf Hallstromin Katu 2, Helsinki 00560, Finland.; Zickermann, V (reprint author), Goethe Univ Frankfurt, Med Sch, Inst Biochem 2, Struct Bioenerget Grp, Max von Laue Str 9, D-60438 Frankfurt, Germa

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2019; 1860 (7): 573

Abstract

Respiratory complex I catalyses the reduction of ubiquinone (Q) from NADH coupled to proton pumping across the inner membrane of mitochondria. The ele......

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