Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency

Liao, D; Chen, WM; Tan, CY; Wong, JX; Chan, PS; Tan, LW; Foo, R; Jiang, JM

Jiang, JM (reprint author), Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, Singapore 117597, Singapore.; Jiang, JM (reprint author), Natl Univ Hlth Syst, Ctr Translat Med, Cardiovasc Res inst, Singapore 117599, Singapore.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

Truncating variants in TTN (TTNtv), coding for the largest structural protein in the sarcomere, contribute to the largest portion of familial and ambu......

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