Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBP alpha to prevent Trib1-driven acute myeloid leukemia

Nakamae, I; Kato, J; Yokoyama, T; Ito, H; Yoneda-Kato, N

Yoneda-Kato, N (reprint author), Nara Inst Sci & Technol, Grad Sch Biol Sci, 8916-5 Takayama, Ikoma, Nara 6300101, Japan.

BLOOD ADVANCES, 2017; 1 (20): 1682

Abstract

C/EBP alpha is a key transcription factor regulating myeloid differentiation and leukemogenesis. The Trib1-COP1 complex is an E3 ubiquitin ligase that......

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