Transduction profiles in minipig following MRI guided delivery of AAV-5 into thalamic and corona radiata areas

Pietersz, KL; Pouw, S; Klima, J; Ellederova, Z; Bohuslavova, B; Chrastina, J; Liscak, R; Urgosik, D; Starek, Z; Crha, M; Lewis, O; Wooley, M; Johnson, D; Brouwers, CC; Evers, M; Motlik, J; Martens, GJM; Konstantinova, PS; Blits, B

Blits, B (通讯作者)，Sana Gen, Amsterdam, Netherlands.

JOURNAL OF NEUROSCIENCE METHODS, 2022; 365 ():

Abstract

Background: As a step towards clinical use of AAV-mediated gene therapy, brains of large animals are used to settle delivery parameters as most brain ......

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