Accurate proteome-wide missense variant effect prediction with AlphaMissense

Cheng, J; Novati, G; Pan, J; Bycroft, C; Zemgulyte, A; Applebaum, T; Pritzel, A; Wong, LH; Zielinski, M; Sargeant, T; Schneider, RG; Senior, AW; Jumper, J; Hassabis, D; Kohli, P; Avsec, Z

Cheng, J; Kohli, P; Avsec, Z (通讯作者),Google DeepMind, London, England.

SCIENCE, 2023; 381 (6664): 1303

Abstract

The vast majority of missense variants observed in the human genome are of unknown clinical significance. We present AlphaMissense, an adaptation of A......

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