SHIP-1 Regulates Phagocytosis and M2 Polarization Through the PI3K/Akt-STAT5-Trib1 Circuit in Pseudomonas aeruginosa Infection

Qin, SG; Li, JX; Zhou, CM; Privratsky, B; Schettler, J; Deng, X; Xia, ZW; Zeng, Y; Wu, H; Wu, M

Wu, M (corresponding author), Univ North Dakota, Sch Med & Hlth Sci, Dept Biomed Sci, Grand Forks, ND 58202 USA.; Zeng, Y; Wu, H (corresponding author), Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu, Peoples R China.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

SHIP-1 is an inositol phosphatase that hydrolyzes phosphatidylinositol 3-kinase (PI3K) products and negatively regulates protein kinase B (Akt) activi......

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