A 5 ' Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo

Lu, JM; Williams, JA; Luke, J; Zhang, FJ; Chu, K; Kay, MA

Kay, MA (reprint author), Dept Pediat, 269 Campus Dr,Room 2105, Stanford, CA 94305 USA.; Kay, MA (reprint author), Dept Genet, 269 Campus Dr,Room 2105, Stanford, CA 94305 USA.

HUMAN GENE THERAPY, 2017; 28 (1): 125

Abstract

We previously developed a mini-intronic plasmid (MIP) expression system in which the essential bacterial elements for plasmid replication and selectio......

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