Von Hippel-Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein

Frost, J; Rocha, S; Ciulli, A

Ciulli, A (corresponding author), Div Biol Chem & Drug Discovery, Dundee, Scotland.; Rocha, S (corresponding author), Univ Dundee, Ctr Gene Regulat & Express, Sch Life Sci, Dundee, Scotland.; Rocha, S (corresponding author), Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol Physiol & Cell Signalling, Liverpool, Merseyside, England.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 297 (2):

Abstract

Von Hippel-Lindau (VHL) disease is characterized by frequent mutation of VHL protein, a tumor suppressor that functions as the substrate recognition s......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索