Eur Radiol:如何有效地评估糖尿病外周神经病变呢?

2017-11-19 shaosai MedSci原创

糖尿病周围神经病是糖尿病最常见的慢性并发症。本研究旨在验证定量的胫神经T2值在诊断糖尿病外周神经病变(DPN)的价值,并将结果发表在Eur Radiol上。

糖尿病周围神经病是糖尿病最常见的慢性并发症。本研究旨在验证定量的胫神经T2值在诊断糖尿病外周神经病变(DPN)的价值,并将结果发表在Eur Radiol上。

本研究共纳入了22例有DPN的糖尿病患者、20例无DPN的糖尿病患者及20名健康志愿者并行胫神经MR成像及T2mapping。测量胫神经T2值并利用Mann-Whitney U检验进行比较。利用ROC分析验证T2值诊断DPN的价值。

在DPN患者组、无DPN患者组及健康志愿者组神经T2值分别为55.06 ± 4.05 ms、48.91 ± 3.06 ms、45.61 ± 1.86 ms。DPN患者组T2值要明显高于无DPN患者组(P < 0.001)。无DPN患者组T2值要明显高于健康志愿者组(P < 0.001)。ROC分析表明T2值鉴别DPN与无DPN的患者及健康志愿者的敏感性、特异性及曲线下面积分别为81.8 %、89.2 % 、0.922,最佳截断值为51.34 ms。

本研究表明,胫神经的T2值可作为评价糖尿病患者DPN的可选择性、非侵入性定量参数。

原始出处:


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    2017-11-23 lou.minghong

    学习了谢谢分享!

    0

  2. 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    2017-11-21 axin012
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  4. 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    2017-11-20 戒馋,懒,贪

    谢谢分享学习了

    0

  5. 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    2017-11-20 明月清辉

    谢谢分享.学习了

    0

  6. 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    2017-11-20 明月清辉

    谢谢分享.学习了

    0

  7. 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    2017-11-20 李东泽

    是很好的学习材料.不错.以后会多学习.

    0

  8. 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    2017-11-19 惠映实验室

    学习了.谢谢.

    0

  9. 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    2017-11-19 有备才能无患

    糖尿病周围神经病是糖尿病最常见的慢性并发症.本研究旨在验证定量的胫神经T2值在诊断糖尿病外周神经病变(DPN)的价值.并将结果发表在EurRadiol上.

    0

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