Diabetes Care:COVID-19期间2型糖尿病老年人抑郁、孤独和失眠患病率变化情况

2021-12-23 MedSci原创 MedSci原创

在COVID-19期间,老年糖尿病患者轻度或中度抑郁症状的患病率是COVID-19大流行之前的1.6倍以上。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在评估2016年至2020年期间2型糖尿病老年患者抑郁症状、孤独感和失眠的患病率变化情况,并评估这些疾病的危险因素,包括人口统计学、多发病率、BMI、治疗等。

这是一项针对AHEAD(糖尿病健康行动)队列研究参与者的前瞻性观察性研究。数据来自COVID-19之前的两次评估(随访1:2016年4月至2018年6月和随访2:2018年2月至2020年2月)和COVID-19期间的一次评估(随访3:2020年7月至12月)。研究人员对受试者进行了调查以评估抑郁症状、孤独感和失眠情况。

该研究纳入了2829名成年人(63.2%为女性,60.6%为白人,平均[SD]年龄为75.6[6.0]岁)。在两次大流行前随访之间,轻度或重度抑郁症状的患病率没有显著变化(P=0.88),但从COVID-19前到COVID-19流行期间显著增加(V2时为19.3%,V3时为30.4%;P<0.001)。

V3时较高的发生轻度或严重抑郁症状几率与女性(调整后的比值比[OR为1.4[95%CI为1.1-1.7]),非西班牙裔白人(OR为1.4[95%CI为1.1-1.7]))、肥胖(OR为1.3[95%CI为1.0-1.5])相关,此外也与在V1(OR为4.0[95%CI为2.9–5.4])、V2(OR为4.4[95%CI为3.2-5.9])或两次随访(OR为13.4[95%CI为9.7-18.4])均报告轻度或更严重抑郁症状相关。孤独感的患病率从V1时的12.3%增加到V3时的22.1%(P<0.001),而失眠的患病率在随访期间保持稳定在31.5-33.3%。

由此可见,在COVID-19期间,老年糖尿病患者轻度或中度抑郁症状的患病率是COVID-19大流行之前的1.6倍以上。

原始出处:
 
Ariana M. Chao,et al.Changes in the Prevalence of Symptoms of Depression, Loneliness, and Insomnia in U.S. Older Adults With Type 2 Diabetes During the COVID-19 Pandemic: The Look AHEAD Study.Diabetes care.2021.https://diabetesjournals.org/care/article/doi/10.2337/dc21-1179/138968/Changes-in-the-Prevalence-of-Symptoms-of

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