J Perinatol:高风险疤痕子宫可行阴道分娩?

2014-11-21 shchjcuky 丁香园

2010年3月后美国国立卫生研究院共识发展会议上的发言公布,剖腹产后阴道分娩(VBAC)的观点存在很大差距。对于剖宫产后女性存在高风险状况(如肥胖、高血压或糖尿病),患者可考虑不行阴道分娩。这些女性最容易发生外科并发症,如伤口感染,分离或静脉血栓栓塞。 近来,美国辛辛那提大学医学院的J Regan等在Journal of Perinatology上发表了一篇文章,其目的是研究剖宫产术后高风险患者

2010年3月后美国国立卫生研究院共识发展会议上的发言公布,剖腹产后阴道分娩(VBAC)的观点存在很大差距。对于剖宫产后女性存在高风险状况(如肥胖、高血压糖尿病),患者可考虑不行阴道分娩。这些女性最容易发生外科并发症,如伤口感染,分离或静脉血栓栓塞

近来,美国辛辛那提大学医学院的J Regan等在Journal of Perinatology上发表了一篇文章,其目的是研究剖宫产术后高风险患者阴道分娩是否可行。

该研究以人群为基础,纳入了2006-2007年美国俄亥俄州分娩的高风险患者。高风险的定义为单胎妊娠,孕龄大于20周,小于42周,有剖宫产史,有相关风险因素(体重指数BMI≥30,高血压糖尿病)。

研究人员发现,一些高风险的有剖宫产史的女性患有高血压,糖尿病或肥胖尝试阴道分娩只有16.6%。尽管这样,高风险的女性尝试阴道分娩,其成功率较高(68.0%)。研究发现,在这个高危人群中,超过IOM孕期体重与VBAC成负相关。

以下因素并未与VBAC相关:人种、产妇年龄、婚姻状况、医疗保险类型、香烟用法、出生体重和胎龄。尽管,人群存在的已知相关风险包括子宫破裂、输血、子宫炎及手术损伤。

在这个高危人群中尝试阴道分娩失败比率是令人鼓舞的。尽量减少失败的并发症,仔细选择那些最有可能实现阴道分娩的高风险女性可以防止一些严重的并发症包括已知与手术相关联的高危人群。

几个已发表的研究报告称,女性的一些个别高风险状况有VBAC的下降率。具体来说,女性有先兆子痫,孕前和妊娠期糖尿病,肥胖和那些过度孕期体重增加妇女,已经报道了具有更高尝试阴道分娩失败率。

总之,即使在高血压,糖尿病和/或肥胖,怀孕期间体重增加的高风险的条件下,VBAC也是安全和可行的。研究中的高危患者队列在尝试阴道分娩后转剖宫产,其并发症(子宫破裂、输血、计划外子宫切除术以及进入重症监护病房)的发生率与低风险女性类似。

原始出处

Regan J1, Keup C1, Wolfe K1, Snyder C1, DeFranco E2.Vaginal birth after cesarean success in high-risk women: a population-based study.J Perinatol. 2014 Oct 23.

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    2015-10-11 feather89
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    2015-05-07 chaie1217

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    0

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    2015-02-18 liye789132251
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    2014-11-23 linlin2312
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    2014-11-23 HinsMax
  7. [GetPortalCommentsPageByObjectIdResponse(id=1725675, encodeId=63901e2567508, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 11 00:15:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22842, encodeId=889e2284233, content=~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Thu May 07 01:18:00 CST 2015, time=2015-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861980, encodeId=35251861980c6, content=<a href='/topic/show?id=a374102813a1' target=_blank style='color:#2F92EE;'>#高风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102813, encryptionId=a374102813a1, topicName=高风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Wed Feb 11 20:15:00 CST 2015, time=2015-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880380, encodeId=a4961880380e9, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Feb 18 14:15:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275046, encodeId=745a12e50461d, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Sun Nov 23 02:15:00 CST 2014, time=2014-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394100, encodeId=30b21394100ec, content=<a href='/topic/show?id=7b29e0460b1' target=_blank style='color:#2F92EE;'>#疤痕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70460, encryptionId=7b29e0460b1, topicName=疤痕)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qXbLjJB4FSzhQS3C5qQFMJkqicRIJFL6zHFwwhv0I95nzA6xicevQcEica0gk4A58UkbMMriadAgTY2b7N7Yd0ZsQg/132, createdBy=910c2500152, createdName=HinsMax, createdTime=Sun Nov 23 02:15:00 CST 2014, time=2014-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485864, encodeId=fcf7148586454, content=<a href='/topic/show?id=57a09e573d0' target=_blank style='color:#2F92EE;'>#阴道分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97573, encryptionId=57a09e573d0, topicName=阴道分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c548060345, createdName=ms3297076796458174, createdTime=Sun Nov 23 02:15:00 CST 2014, time=2014-11-23, status=1, ipAttribution=)]