(原创)低位直肠癌TNM分期的争议

2017-01-18 温医一院 李绍堂 全球结直肠医学高峰论坛

进行MDT讨论时,往往外科专家和影像学专家使用的分期标准不同,对低位直肠癌的术前评估产生差异。所以,笔者认为有必要利用解剖学结合影像学对低位直肠癌T分期给与统一的标准。

近期UICC发布结直肠癌TNM分期新版本(第8版),将于2018年1月应用于临床。但是,仍然没有关注低位直肠癌的分期。由于低位直肠周围组织不同于高位直肠及结肠周围组织。所以它的分期并不能完全套用UICC的TNM分期中的T分期。况且,目前临床上的各大指南(NCCN, ESMO,中国结直肠诊疗指南)也没有给低位直肠癌明确的T分期标准。所以不同的文献资料对T分期存在不同的描述。进行MDT讨论时,往往外科专家和影像学专家使用的分期标准不同,对低位直肠癌的术前评估产生差异。所以,笔者认为有必要利用解剖学结合影像学对低位直肠癌T分期给与统一的标准。首先我们要明确一下低位直肠癌的定义。从解剖学角度来区分,以腹膜反折为界将直肠分为上段(高位)和下段(低位)直肠。我们这里讨论的低位直肠癌引用解剖学定义标准。目前,临床上低位直肠癌的术前评估最重要的是需要MRI和直肠腔内超声检查。其中直肠MRI的报告方面,影像学专家大多数采用标准的“DISTANCE”方法[1-3]。该方法对低位直肠癌“T”,也就是T分期进行了描述。该标准认为:T1,肿瘤局限于肌层(图1,2);T2,肿瘤侵透全肌层但未侵及括约肌间隙(图3,

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1952221, encodeId=41f119522211b, content=<a href='/topic/show?id=d62f1e60618' target=_blank style='color:#2F92EE;'>#TNM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17606, encryptionId=d62f1e60618, topicName=TNM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e183245, createdName=Eleven11, createdTime=Sat Nov 25 13:53:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173527, encodeId=22ff1e352746, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Wed Feb 01 06:00:19 CST 2017, time=2017-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172435, encodeId=16131e243510, content=感谢分享,学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Tue Jan 24 23:29:41 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171563, encodeId=47c61e1563f2, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Fri Jan 20 10:48:25 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376667, encodeId=0c2513e66677d, content=<a href='/topic/show?id=c0261e607d0' target=_blank style='color:#2F92EE;'>#TNM分期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17607, encryptionId=c0261e607d0, topicName=TNM分期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb32388, createdName=linne320, createdTime=Fri Jan 20 01:53:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171433, encodeId=e4551e1433ce, content=不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Jan 19 21:30:52 CST 2017, time=2017-01-19, status=1, ipAttribution=)]
    2017-11-25 Eleven11
  2. [GetPortalCommentsPageByObjectIdResponse(id=1952221, encodeId=41f119522211b, content=<a href='/topic/show?id=d62f1e60618' target=_blank style='color:#2F92EE;'>#TNM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17606, encryptionId=d62f1e60618, topicName=TNM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e183245, createdName=Eleven11, createdTime=Sat Nov 25 13:53:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173527, encodeId=22ff1e352746, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Wed Feb 01 06:00:19 CST 2017, time=2017-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172435, encodeId=16131e243510, content=感谢分享,学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Tue Jan 24 23:29:41 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171563, encodeId=47c61e1563f2, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Fri Jan 20 10:48:25 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376667, encodeId=0c2513e66677d, content=<a href='/topic/show?id=c0261e607d0' target=_blank style='color:#2F92EE;'>#TNM分期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17607, encryptionId=c0261e607d0, topicName=TNM分期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb32388, createdName=linne320, createdTime=Fri Jan 20 01:53:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171433, encodeId=e4551e1433ce, content=不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Jan 19 21:30:52 CST 2017, time=2017-01-19, status=1, ipAttribution=)]
    2017-02-01 卡圣

    长见识了

    0

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    2017-01-24 cqykthl

    感谢分享,学习到了

    0

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    2017-01-20 李东泽

    很好,不错,以后会多学习

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1952221, encodeId=41f119522211b, content=<a href='/topic/show?id=d62f1e60618' target=_blank style='color:#2F92EE;'>#TNM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17606, encryptionId=d62f1e60618, topicName=TNM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e183245, createdName=Eleven11, createdTime=Sat Nov 25 13:53:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173527, encodeId=22ff1e352746, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Wed Feb 01 06:00:19 CST 2017, time=2017-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172435, encodeId=16131e243510, content=感谢分享,学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Tue Jan 24 23:29:41 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171563, encodeId=47c61e1563f2, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Fri Jan 20 10:48:25 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376667, encodeId=0c2513e66677d, content=<a href='/topic/show?id=c0261e607d0' target=_blank style='color:#2F92EE;'>#TNM分期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17607, encryptionId=c0261e607d0, topicName=TNM分期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb32388, createdName=linne320, createdTime=Fri Jan 20 01:53:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171433, encodeId=e4551e1433ce, content=不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Jan 19 21:30:52 CST 2017, time=2017-01-19, status=1, ipAttribution=)]
    2017-01-19 1e1263e3m20(暂无匿称)

    不错学习了

    0

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