Crit Care Med:MRI在创伤性脑损伤中的预后价值如何?

2017-10-26 MedSci MedSci原创

创伤性脑损伤是死亡和残疾的主要原因,但现有的许多预测结果不足以指导初步的临床决策。虽然在创伤性脑损伤后的早期阶段,越来越多使用MRI,但其预后效用仍然不确定。近期,一项发表在杂志Crit Care Med上的研究进行了系统评价和荟萃分析,以评估急性MRI损伤模式对区分创伤性脑损伤的临床结局的预测价值。此项研究的数据来源于MEDLINE,EMBASE,BIOSIS和CENTRAL数据库,自研究开始到

创伤性脑损伤是死亡和残疾的主要原因,但现有的许多预测结果不足以指导初步的临床决策。虽然在创伤性脑损伤后的早期阶段,越来越多使用MRI,但其预后效用仍然不确定。近期,一项发表在杂志Crit Care Med上的研究进行了系统评价和荟萃分析,以评估急性MRI损伤模式对区分创伤性脑损伤的临床结局的预测价值。此项研究的数据来源于MEDLINE,EMBASE,BIOSIS和CENTRAL数据库,自研究开始到2015年11月。受试对象为在中度或重度创伤性脑损伤后急性期MRI患者的研究。此项研究的主要结果是全因死亡率和格拉斯哥结果量表。由两位研究者独立进行研究选择和数据提取。使用随机效应模型计算汇总效应估计值,使用预后研究中的质量修改版本评估偏倚风险,并用建议、评估、开发和评估等级确定证据的强度。最终,此项研究包括了58项研究,其中27项(n = 1,652)为荟萃分析。大于或等于6个月时,脑干病变与全因死亡率(风险比为1.78; 95%CI,1.01-3.15;I = 43%)以及不利的格拉斯哥结果量表相关(风险比为2.49;95%CI为1.72-3.58;I = 81 %)。弥漫性轴索损伤模式与

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    2018-08-09 wanghx2006

    (??ω?)?嘿

    0

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    2017-12-10 amyloid
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