Ann Rheum Dis:银屑病和类风湿性关节炎患者健康相关的生活质量

2018-06-10 xiangting MedSci原创

总体上RA和PsA患者的健康相关生活质量相似,其中PsA有评分更差的趋势。

这项研究旨在比较:(1)类风湿性关节炎(RA)、银屑病关节炎(PsA)患者和挪威一般对照人群的SF-36量表生理健康总分(PCS)和精神健康总分(MCS)、量表评分和SF-6维(SF-6D);(2)RA和PsA患者这些指标的改善。

进行协方差分析以比较RA患者(n=3898)、PsA患者(n= 1515)和一般人群对照(n=2323)的SF-36指标。患者来自前瞻性观察性多中心挪威-疾病改善抗风湿药研究(随访6个月),这些患者为首次入选。

在调整年龄和性别的分析中,PsA患者与RA患者的PCS、MCS和SF-6D相似(p≥0.14),生命力和总体健康状况较差,但在0/6个月时身体功能较好(p≤ 0.03)。调整28-关节疾病活动评分代表关节炎症后,0/3/6个月PsA患者的PCS、大多数量表评分和SF-6D均低于RA患者(p≤0.01)。与一般人群对照相比,RA和PsA患者的PCS比MCS受损更重(p≤0.001)。RA患者疾病改善抗风湿药物治疗后身体疼痛、生命力和心理健康平均3个月和6个月的改善均大于PsA患者(p≤0.02)。

总体上RA和PsA患者的健康相关生活质量相似,其中PsA有评分更差的趋势。与挪威一般人群对照相比,两者评分更差。


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    2018-06-12 清风拂面

    谢谢分享学习

    0

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    2018-06-12 lmm397
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    2018-06-10 清风拂面

    谢谢分享学习

    0

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