Neurology:多发性硬化症妇女的围产期抑郁和焦虑现状分析

2021-04-22 MedSci原创 MedSci原创

确诊为MS的妇女围产期抑郁的风险增加。在妊娠后5年内经历MS症状发作的妇女,在妊娠期间患抑郁症和焦虑症的风险增加。

近日,神经病学领域权威杂志Neurology上发表了一篇研究文章,该研究旨在评估多发性硬化症(MS)诊断之前和之后的女性围产期抑郁症和焦虑症的发生率。

在1999-2008年期间,研究人员纳入了挪威母亲、父亲和儿童队列研究中的114629名孕妇。研究人员在受试者妊娠期间和之后通过问卷评估了抑郁和焦虑水平,并从国家卫生登记中心和医院记录中识别出患有MS的女性,并将其分为以下几类:1)妊娠前确诊的MS(n=140),2)妊娠前症状发作,但在妊娠后确诊的MS(n=98),以及3)妊娠后症状发作并在妊娠后确诊的MS(n=308)。

在产后期间,有35名妇女被诊断出MS。参照组(n=111627)为无MS的女性。

妊娠前诊断为MS的女性在妊娠中期发生抑郁的调整后比值比为2.0(95%置信区间为1.2-3.1)。危险因素包括不利的社会经济因素、精神病史和身体/性虐待。焦虑的风险没有增加。产后被诊断患有MS的妇女产后抑郁的风险特别高。妊娠后5年内伴有MS症状发作的女性在妊娠期间患抑郁和焦虑的风险增加,而症状发生前超过5年的女性则不然。

由此可见,确诊为MS的妇女围产期抑郁的风险增加。在妊娠后5年内经历MS症状发作的妇女,在妊娠期间患抑郁症和焦虑症的风险增加

原始出处:

Karine Eid.et al.Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study.Neurology.2021.https://doi.org/10.1212/WNL.0000000000012062

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    2021-07-14 jml2009
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    2022-02-06 yinhl1978
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  5. 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  6. 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    2021-04-23 科研科研科研

    多发性硬化症

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=959581, encodeId=1f4d959581d2, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:12:01 CST 2021, time=2021-04-22, status=1, ipAttribution=)]
    2021-04-22 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210110/e6124a4b19bc40ce8afaae096d21126b/dd778ac260c9416eb87e7d08139507f5.jpg, createdBy=4d2f5079605, createdName=科研科研科研, createdTime=Fri Apr 23 12:10:42 CST 2021, time=2021-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050554, encodeId=46661050554e7, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Thu Apr 22 23:15:40 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959584, encodeId=c6a695958495, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/3R8FMszG3GZeyJibevd47qA9Uts6OHxaxycFUGMj8MSA1Lj2HSVgkxibmoTcvjjVaQwtljvI3t5sS0ngQvia3zr4Q/132, createdBy=a9185155976, createdName=朱朱zl, createdTime=Thu Apr 22 21:29:29 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959582, encodeId=5d61959582f4, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:14:36 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959581, encodeId=1f4d959581d2, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:12:01 CST 2021, time=2021-04-22, status=1, ipAttribution=)]
    2021-04-22 朱朱zl

    #学习#学到了

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210110/e6124a4b19bc40ce8afaae096d21126b/dd778ac260c9416eb87e7d08139507f5.jpg, createdBy=4d2f5079605, createdName=科研科研科研, createdTime=Fri Apr 23 12:10:42 CST 2021, time=2021-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050554, encodeId=46661050554e7, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Thu Apr 22 23:15:40 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959584, encodeId=c6a695958495, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/3R8FMszG3GZeyJibevd47qA9Uts6OHxaxycFUGMj8MSA1Lj2HSVgkxibmoTcvjjVaQwtljvI3t5sS0ngQvia3zr4Q/132, createdBy=a9185155976, createdName=朱朱zl, createdTime=Thu Apr 22 21:29:29 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959582, encodeId=5d61959582f4, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:14:36 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959581, encodeId=1f4d959581d2, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:12:01 CST 2021, time=2021-04-22, status=1, ipAttribution=)]
    2021-04-22 Waterxu

    感谢分享

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210110/e6124a4b19bc40ce8afaae096d21126b/dd778ac260c9416eb87e7d08139507f5.jpg, createdBy=4d2f5079605, createdName=科研科研科研, createdTime=Fri Apr 23 12:10:42 CST 2021, time=2021-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050554, encodeId=46661050554e7, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Thu Apr 22 23:15:40 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959584, encodeId=c6a695958495, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, 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GetPortalCommentsPageByObjectIdResponse(id=959581, encodeId=1f4d959581d2, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/rUNeEPz0A57BPb8Sn156gJ6uBeTibJsvqcJyvIXkjz7xLdsicATibffsY9af7xER2UEYdg7ygN9HRTp7nPcp8D8IA/132, createdBy=04092497669, createdName=Waterxu, createdTime=Thu Apr 22 21:12:01 CST 2021, time=2021-04-22, status=1, ipAttribution=)]
    2021-04-22 Waterxu

    感谢分享

    0

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每天一杯热可可,不仅改善血管功能...

在精神紧张时,喝一杯含有高水平黄烷醇的可可饮料比喝其他饮料更有益于血管功能。

Neurology:多发性硬化:不同临床分型,对应的灰质受累类型各有不同

Neurology:多发性硬化:不同临床分型,对应的灰质受累类型各有不同

Cell Death Differ:NDP52突变能够促进线粒体自噬并抑制多发性硬化症中的炎症反应

多发性硬化症(MS)是一种自身免疫性疾病,其能够引起中枢神经系统的慢性炎症反应,导致脱髓鞘和轴突的损伤,最终导致运动、感觉和认知的丧失。

JNNP:临床孤立综合征,脑萎缩者的死亡和残疾率更高

临床孤立综合征,5年内的脑区域萎缩可预测死亡和残疾

JNNP:线性法测量多发性硬化和临床孤立综合征的脑萎缩:一项30年随访研究

多发性硬化症(MS)是一种中枢神经系统的慢性炎症、脱髓鞘和神经退行性疾病。大约85%的MS患者最初患有复发-缓解型(RR)MS,这与炎症性脱髓鞘病变的发生有关,从长期来看,大多数患者会发展为继发性进行