阻塞性睡眠呼吸暂停门诊手术:十大要点

2015-10-13 大鹏 译 医学论坛网

本文汇总了阻塞性睡眠呼吸暂停(OSA)门诊手术治疗应注意的十个要点,涵盖了OSA围手术评估及治疗。全文发表于《胸》(Chest)杂志上。 一、指南 1.相当一部分医院的OSA患者门诊手术后当天出院的比例可达70%。 2.已往的医疗习惯为,OSA患者术后需入重症监护病房观察。但是除了非五官科择期手术患者,尚无确凿证据证实OSA是意外入院的独立风险因素。 3.门诊麻醉协会2

本文汇总了阻塞性睡眠呼吸暂停(OSA)门诊手术治疗应注意的十个要点,涵盖了OSA围手术评估及治疗。全文发表于《胸》(Chest)杂志上。

一、指南

1.相当一部分医院的OSA患者门诊手术后当天出院的比例可达70%。

2.已往的医疗习惯为,OSA患者术后需入重症监护病房观察。但是除了非五官科择期手术患者,尚无确凿证据证实OSA是意外入院的独立风险因素。

3.门诊麻醉协会2012年指南推荐,只要OSA患者术后能够遵医嘱接受持续气道正压通气治疗,那么优化并存病后的此类患者是门诊外科手术可以接受的风险。

4.现行指南亦强调,对于所有门诊外科手术患者,临床医生需监测其有无OSA。虽然尚无证据支持此举确能改善患者预后。

二、术前检查

5.多导睡眠图是诊断OSA的金标准,但除了重度OSA患者群体(AHI>30事件/小时),尚无证据证实较高的呼吸暂停低通气指数(AHI)与不良预后相关。可能的原因包括患者夜间变化度影响,不同实验室评估标准存在差异,患者睡姿影响评分。

6.家庭睡眠检测性价比越来越高,且操作更为简便,但由于缺乏陪同者纠正信号错误,此检测的失败率达20%。

7.即使患者术前已确诊OSA,且接受治疗,不能武断认为OSA会影响患者预后。

三、OSA治疗

8.重度OSA患者或存在的严重并发症包括,镇静或诱导过程中出现上气道阻塞,插管失败,负压性肺水肿,心律失常,缺氧型心搏骤停。

9.在OSA患者治疗方案中,尚无单一药物治疗被证实优于诱导麻醉。

10.需进一步研究证实OSA术后AHI水平是否能得到控制。

参考文献:

Stierer TL, Collop NA.Perioperative Assessment and Management for Sleep Apnea in the Ambulatory Surgical Patient. Chest 2015

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    2016-06-17 zz70
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    2015-12-31 忠诚向上

    要注意

    0

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    2015-12-23 tomyang96
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1988118, encodeId=92e4198811850, content=<a href='/topic/show?id=4bce9e1280e' target=_blank style='color:#2F92EE;'>#门诊手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97128, encryptionId=4bce9e1280e, topicName=门诊手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Jun 17 22:57:00 CST 2016, time=2016-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50771, encodeId=c09550e7101, content=要注意, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Dec 31 12:47:00 CST 2015, time=2015-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696655, encodeId=0fa71696655f6, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Dec 23 00:57:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988991, encodeId=0a171988991cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Dec 26 09:57:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39274, encodeId=f7a1392e4c1, content=赞一个~, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39275, encodeId=a29d392e500, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39276, encodeId=83af392e6e2, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596447, encodeId=2d9f159644ece, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Oct 14 23:57:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2015-10-18 sunlong28

    赞一个~

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1988118, encodeId=92e4198811850, content=<a href='/topic/show?id=4bce9e1280e' target=_blank style='color:#2F92EE;'>#门诊手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97128, encryptionId=4bce9e1280e, topicName=门诊手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Jun 17 22:57:00 CST 2016, time=2016-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50771, encodeId=c09550e7101, content=要注意, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Dec 31 12:47:00 CST 2015, time=2015-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696655, encodeId=0fa71696655f6, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Dec 23 00:57:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988991, encodeId=0a171988991cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Dec 26 09:57:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39274, encodeId=f7a1392e4c1, content=赞一个~, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39275, encodeId=a29d392e500, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39276, encodeId=83af392e6e2, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596447, encodeId=2d9f159644ece, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Oct 14 23:57:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2015-10-18 sunlong28

    谢谢分享~

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1988118, encodeId=92e4198811850, content=<a href='/topic/show?id=4bce9e1280e' target=_blank style='color:#2F92EE;'>#门诊手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97128, encryptionId=4bce9e1280e, topicName=门诊手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Jun 17 22:57:00 CST 2016, time=2016-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50771, encodeId=c09550e7101, content=要注意, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Dec 31 12:47:00 CST 2015, time=2015-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696655, encodeId=0fa71696655f6, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Dec 23 00:57:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988991, encodeId=0a171988991cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Dec 26 09:57:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39274, encodeId=f7a1392e4c1, content=赞一个~, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39275, encodeId=a29d392e500, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39276, encodeId=83af392e6e2, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596447, encodeId=2d9f159644ece, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Oct 14 23:57:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2015-10-18 sunlong28

    为了积分我也是拼了~

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1988118, encodeId=92e4198811850, content=<a href='/topic/show?id=4bce9e1280e' target=_blank style='color:#2F92EE;'>#门诊手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97128, encryptionId=4bce9e1280e, topicName=门诊手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Jun 17 22:57:00 CST 2016, time=2016-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50771, encodeId=c09550e7101, content=要注意, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Dec 31 12:47:00 CST 2015, time=2015-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696655, encodeId=0fa71696655f6, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Dec 23 00:57:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988991, encodeId=0a171988991cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Dec 26 09:57:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39274, encodeId=f7a1392e4c1, content=赞一个~, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39275, encodeId=a29d392e500, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39276, encodeId=83af392e6e2, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:15:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596447, encodeId=2d9f159644ece, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Oct 14 23:57:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]

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摘要阻塞性睡眠呼吸暂停是睡眠过程中上气道反复塌陷,造成血氧饱和度下降以及睡眠中断,正成为越来越常见的疾病。其症状包括打鼾、呼吸暂停以及白天嗜睡。阻塞性睡眠呼吸暂停的发病机制各异,易感因素包括上呼吸气道狭小、 呼吸调节不稳定、 唤醒阈值低、肺容量小和上呼吸道扩张肌功能失调。危险因素包括肥胖、 男性、 年龄、 更年期、 体液潴留、 扁桃体肥大和吸烟。阻塞性睡眠呼吸暂停能引起白天嗜睡、 道路交通事故,并

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由加拿大卡尔加里大学的Marcus Povitz、 Carmelle Bolo及其同事发表在本周的《公共科学图书馆·医学》(PLOS Medicine)杂志上的一项研究发现,用连续气道正压通气(CPAP)或者下颌前移装置(MADs)治疗阻塞性睡眠呼吸暂停的疗法可能会轻度改善抑郁症的症状。 这组科研人员鉴别出了22个随机化对照试验,这些试验研究了连续气道正压

J Clin Sleep Med:阻塞性睡眠呼吸暂停或可增加患者癌症风险

癌症可能是需要添加到阻塞性睡眠呼吸暂停(OSA)风险列表中的另一类疾病。在20年的随访期间,睡眠呼吸暂停患者的癌症死亡率较无睡眠呼吸暂停者高3.4倍。以上是澳大利亚悉尼大学护理学院Marshall博士等人近期一项研究得出的主要结论。该项基于人口的纵向研究显示,在对肥胖和各种其他因素进行了统计学校正后,中、重度OSA与患者癌症发生风险2.5倍的增高相关。研究报告发表在2014年4月15日的J Cli

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DiabetesCare 2013年9月23日在线版发布了英国伯明翰大学AbdA.Tahrani等开展的一项队列研究,研究显示,伴阻塞性睡眠呼吸暂停(OSA)的2型糖尿病患者发生肾病的风险是无糖尿病者的2.64倍。 在该研究中,糖尿病肾病(DN)定义为:出现白蛋白尿或估算肾小球滤过率(eGFR)<60ml/min/1.73m2;OSA定义为:呼吸暂停低通气指数(AHI)≥5次/h。在纳入研

JAMA:合并OSA的顽固性高血压患者持续气道正压通气可获益

超过70%的难治性高血压患者有阻塞性睡眠呼吸暂停(OSA),但鲜有证据表明持续气道正压通气(CPAP)对顽固性高血压(resistant hypertension)患者血压的影响。近期西班牙一项研究表明,在合并OSA的顽固性高血压患者中,CPAP治疗12周可使其24小时平均血压和舒张压以及夜间勺型高血压模式有所改善。相关论文2013年12月11日在线发表于《美国医学会杂志》(JAMA)。