Bioact Mater:Col/HA多层共价固定化TCs可以减少植入物的无菌性松动

2018-05-18 MedSci MedSci原创

种植体的无菌性松动是钛植体植入失败的主要原因之一。在我们以前的工作中,通过层层(LBL)共价固定技术开发了一种新型稳定的胶原/透明质酸(Col/HA)多层改性钛涂层(TCs),与Col/HA物理吸附的TCs相比具有更好的生物学特性。 在这项研究中,研究人员采用兔股骨髁部缺损模型来比较其的骨整合性能。结果表明Col/HA多层膜具有良好的稳定性,可以更好地促进种植体周围的骨形成和骨-种植体接触

种植体的无菌性松动是钛植体植入失败的主要原因之一。在我们以前的工作中,通过层层(LBL)共价固定技术开发了一种新型稳定的胶原/透明质酸(Col/HA)多层改性钛涂层(TCs),与Col/HA物理吸附的TCs相比具有更好的生物学特性。

在这项研究中,研究人员采用兔股骨髁部缺损模型来比较其的骨整合性能。结果表明Col/HA多层膜具有良好的稳定性,可以更好地促进种植体周围的骨形成和骨-种植体接触。

综上所述,该研究结果表明,Col/HA多层共价固定化TCs可以减少植入物的无菌性松动。

原始出处:

Ao H, Zong J, et al., An in vivo study on the effect of coating stability on osteointegration performance of collagen/hyaluronic acid multilayer modified titanium implants. Bioact Mater. 2017 Jul 27;3(1):97-101. doi: 10.1016/j.bioactmat.2017.07.004. eCollection 2018 Mar.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=2016559, encodeId=dea8201655950, content=<a href='/topic/show?id=04cb1e21583' target=_blank style='color:#2F92EE;'>#TCS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17215, encryptionId=04cb1e21583, topicName=TCS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Thu Jul 26 00:09:00 CST 2018, time=2018-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918095, encodeId=d8fc19180958d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Dec 27 02:09:00 CST 2018, time=2018-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321709, encodeId=4003321e09a1, content=好好学习天天向上认真学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Tue Jun 05 19:26:50 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490895, encodeId=a50a1490895fa, content=<a href='/topic/show?id=fb916268636' target=_blank style='color:#2F92EE;'>#植入物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62686, encryptionId=fb916268636, topicName=植入物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38628846382, createdName=linagood, createdTime=Sun May 20 14:09:00 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520481, encodeId=6b541520481ea, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Sun May 20 14:09:00 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316438, encodeId=8c4731643803, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri May 18 23:35:35 CST 2018, time=2018-05-18, status=1, ipAttribution=)]
    2018-07-26 marongnuan
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    2018-12-27 sunylz
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    2018-06-05 zwjnj2

    好好学习天天向上认真学习

    0

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    2018-05-20 jiyangfei
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    2018-05-18 清风拂面

    谢谢分享学习

    0