Dig Dis Sci:腹腔镜胆囊切除术对急性胆管炎患者30天再入院的影响

2021-03-14 MedSci原创 MedSci原创

急性胆管炎是一种严重的胆道感染性疾病,需要及时治疗,急性胆管炎会导致胆道阻塞,进而导致胆管感染。

       急性胆管炎是一种严重的胆道感染性疾病,需要及时治疗,急性胆管炎会导致胆道阻塞,进而导致胆管感染。大多数急性胆管炎病例是由胆总管结石症(28–70%)引起的,2012年,全美约有10,000名因胆总管结石引起的急性胆管炎患者入院,ERCP是急性胆管炎患者的一种治疗方法,可实现胆道引流和胆总管结石摘除,但是接受内镜逆行胰胆管造影术(ERCP)的患者死亡率仍有0.3%。因此,急性胆管炎患者清除胆总管结石后,建议胆结石患者进行腹腔镜胆囊切除术(LC),LC可降低胆道症状的复发,但是,LC对于患者的预后目前还不清楚,因此,本项研究的目的是评估入院时进行LC对患者30天再入院率的影响。

 

 

      研究人员对2013年4月至2018年5月之间通过内镜逆行胰胆管造影术进行了胆管内镜清除术(EC)的急性胆结石性胆管炎患者进行了一项回顾性队列研究。患者分为两组:仅EC组和入院期间先做EC然后做LC 的(EC + LC)组。主要观察结果是30天的再入院率。

 

 

      该分析共纳入了95例急性胆管炎患者。在这些患者中,有35例(36.8%)在入院时接受了LC治疗。EC + LC组的30天再入院率明显低于EC组(2.9% VS 26.7%,P = 0.003)。在多因素回归分析中,入院时接受LC的患者在30天内的再入院率比未接受入院的患者低90%(OR 0.1,95%CI(0.01-0.9),P 0.04)。

 

       因此,本项研究强有力的证明了急性胆结石性胆管炎患者入院期间进行内窥镜清除胆管后进行腹腔镜胆囊切除术可显着降低30天再入院率,而不会影响住院时间。

 

 

 

原始出处:

Muhammad Alsayid. et al. The Impact of Laparoscopic Cholecystectomy on 30-Day Readmission Rate for Acute Cholangitis Patients: A Single-Center Study. Digestive Diseases and Sciences.2021.

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createdName=doctorzheng, createdTime=Tue Aug 17 13:27:45 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679013, encodeId=18d516e901388, content=<a href='/topic/show?id=df0a834328b' target=_blank style='color:#2F92EE;'>#胆囊切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83432, encryptionId=df0a834328b, topicName=胆囊切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d227724361, createdName=huangshifeng, createdTime=Sun Aug 22 17:27:45 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013602, encodeId=953420136027c, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Oct 03 04:27:45 CST 2021, time=2021-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977840, encodeId=7b6519e78403d, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Tue Jan 04 22:27:45 CST 2022, time=2022-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276480, encodeId=e32b12e648099, content=<a href='/topic/show?id=768685612db' target=_blank style='color:#2F92EE;'>#腹腔镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85612, encryptionId=768685612db, topicName=腹腔镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429802, encodeId=383c142980254, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626171, encodeId=2ed816261e14d, content=<a href='/topic/show?id=b1fe856407b' target=_blank style='color:#2F92EE;'>#腹腔镜胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85640, encryptionId=b1fe856407b, topicName=腹腔镜胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628475, encodeId=070916284e5b1, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948445, encodeId=71909484457a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64615469039, createdName=ms5000001524855720, createdTime=Mon Mar 15 19:14:21 CST 2021, time=2021-03-15, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1951442, encodeId=ed2b1951442b4, content=<a href='/topic/show?id=c5fc5241069' target=_blank style='color:#2F92EE;'>#急性胆管炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52410, encryptionId=c5fc5241069, topicName=急性胆管炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Mar 29 08:27:45 CST 2021, time=2021-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877393, encodeId=04b118e739306, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Aug 17 13:27:45 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679013, encodeId=18d516e901388, content=<a href='/topic/show?id=df0a834328b' target=_blank style='color:#2F92EE;'>#胆囊切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83432, encryptionId=df0a834328b, topicName=胆囊切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d227724361, createdName=huangshifeng, createdTime=Sun Aug 22 17:27:45 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013602, encodeId=953420136027c, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Oct 03 04:27:45 CST 2021, time=2021-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977840, encodeId=7b6519e78403d, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Tue Jan 04 22:27:45 CST 2022, time=2022-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276480, encodeId=e32b12e648099, content=<a href='/topic/show?id=768685612db' target=_blank style='color:#2F92EE;'>#腹腔镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85612, encryptionId=768685612db, topicName=腹腔镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429802, encodeId=383c142980254, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626171, encodeId=2ed816261e14d, content=<a href='/topic/show?id=b1fe856407b' target=_blank style='color:#2F92EE;'>#腹腔镜胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85640, encryptionId=b1fe856407b, topicName=腹腔镜胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628475, encodeId=070916284e5b1, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948445, encodeId=71909484457a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64615469039, createdName=ms5000001524855720, createdTime=Mon Mar 15 19:14:21 CST 2021, time=2021-03-15, status=1, ipAttribution=)]
    2022-01-04 smlt2008
  6. [GetPortalCommentsPageByObjectIdResponse(id=1951442, encodeId=ed2b1951442b4, content=<a href='/topic/show?id=c5fc5241069' target=_blank style='color:#2F92EE;'>#急性胆管炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52410, encryptionId=c5fc5241069, topicName=急性胆管炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Mar 29 08:27:45 CST 2021, time=2021-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877393, encodeId=04b118e739306, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Aug 17 13:27:45 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679013, encodeId=18d516e901388, content=<a href='/topic/show?id=df0a834328b' target=_blank style='color:#2F92EE;'>#胆囊切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83432, encryptionId=df0a834328b, topicName=胆囊切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d227724361, createdName=huangshifeng, createdTime=Sun Aug 22 17:27:45 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013602, encodeId=953420136027c, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Oct 03 04:27:45 CST 2021, time=2021-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977840, encodeId=7b6519e78403d, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Tue Jan 04 22:27:45 CST 2022, time=2022-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276480, encodeId=e32b12e648099, content=<a href='/topic/show?id=768685612db' target=_blank style='color:#2F92EE;'>#腹腔镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85612, encryptionId=768685612db, topicName=腹腔镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429802, encodeId=383c142980254, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626171, encodeId=2ed816261e14d, content=<a href='/topic/show?id=b1fe856407b' target=_blank style='color:#2F92EE;'>#腹腔镜胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85640, encryptionId=b1fe856407b, topicName=腹腔镜胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628475, encodeId=070916284e5b1, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948445, encodeId=71909484457a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64615469039, createdName=ms5000001524855720, createdTime=Mon Mar 15 19:14:21 CST 2021, time=2021-03-15, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1951442, encodeId=ed2b1951442b4, content=<a href='/topic/show?id=c5fc5241069' target=_blank style='color:#2F92EE;'>#急性胆管炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52410, encryptionId=c5fc5241069, topicName=急性胆管炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Mar 29 08:27:45 CST 2021, time=2021-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877393, encodeId=04b118e739306, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, 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encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Oct 03 04:27:45 CST 2021, time=2021-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977840, encodeId=7b6519e78403d, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Tue Jan 04 22:27:45 CST 2022, time=2022-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276480, encodeId=e32b12e648099, content=<a href='/topic/show?id=768685612db' target=_blank style='color:#2F92EE;'>#腹腔镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85612, encryptionId=768685612db, topicName=腹腔镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429802, encodeId=383c142980254, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626171, encodeId=2ed816261e14d, content=<a href='/topic/show?id=b1fe856407b' target=_blank style='color:#2F92EE;'>#腹腔镜胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85640, encryptionId=b1fe856407b, topicName=腹腔镜胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Tue Mar 16 12:27:45 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628475, encodeId=070916284e5b1, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Mar 16 12:27:45 CST 2021, 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  8. 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    2021-03-15 ms5000001524855720

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