J Periodontol:有无糖尿病与种植体周真菌的存在与否有关

2019-07-28 sunshine 译 MedSci原创

目前尚未有研究探究2种糖尿病和非糖尿病患者种植体周围炎的龈下口腔生物膜(OB)中真菌的存在。本研究旨在评估具有种植体周围炎的2型糖尿病和非糖尿病患者的龈下OB中真菌的存在。研究纳入种植体周围炎的2型糖尿病患者(A组),种植体周围炎的非糖尿病患者(B组)和没有种植体周围炎的非糖尿病患者(C组)。使用问卷收集生活方式相关和人口统计学数据,并测量血红蛋白A1c水平。评估种植体周围斑块指数(PI),探测出

目前尚未有研究探究2种糖尿病和非糖尿病患者种植体周围炎的龈下口腔生物膜(OB)中真菌的存在。本研究旨在评估具有种植体周围炎的2型糖尿病和非糖尿病患者的龈下OB中真菌的存在。

研究纳入种植体周围炎的2型糖尿病患者(A组),种植体周围炎的非糖尿病患者(B组)和没有种植体周围炎的非糖尿病患者(C组)。使用问卷收集生活方式相关和人口统计学数据,并测量血红蛋白A1c水平。评估种植体周围斑块指数(PI),探测出血(BOP)和探诊深度(PD),并测量牙槽骨损失(CBL)。收集龈下OB样品,并使用ChromAgar培养基鉴定口服酵母物种。显著性水平设定为P <0.05。

结果显示,A组(n = 43),B组(n = 41)和C组(n = 42)患者的平均年龄分别为55.6±6.4,54.6±4.5和57.1±3.3岁。A组平均HbA1c水平(P <0.01)高于B组和C组。与B组和C组患者相比,A组种植体周围PI(P <0.01),BOP(P <0.01),PD(P <0.01)和CBL(P <0.01)均明显升高。种植体周围PI(P <0.05),BOP(P <0.05),PD(P <0.05)和CBL(P <0.05)显着升高B组患者与C组患者相比。龈下真菌通常从A组(74.4%)和B组(46.3%)而不是C组(7.1%)的患者OB中分离出来。在所有组中鉴定的最常见的真菌物种是白色念珠菌。龈下真菌的CFU/ml在A组中高于B组(P <0.01)和C(P <0.01)。龈下真菌的CFU/ml在B组比C组高(P <0.01)。

总之,该研究结果表明,对于没有种植体周围疾病的全身健康个体,2型糖尿病和非糖尿病患者的龈下OB更常出现念珠菌属(主要是白色念珠菌)种植体周围炎。

原始出处:

Alsahhaf A, Al-Aali KA, et al., Comparison of yeasts species in the subgingival oral biofilm of type 2-diabetic and non-diabetic individuals with peri-implantitis. J Periodontol. 2019 Jul 18. doi: 10.1002/JPER.19-0091.

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    2020-05-19 huangdf
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    2020-03-22 feather89
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    2019-07-30 zhaojie88
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    2019-07-28 misszhang

    谢谢MedSci提供最新的资讯

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