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晚期恶性肿瘤的治疗：抗CD47单克隆抗体TJC4在中国启动临床试验

2019-07-15 Allan MedSci原创

抗CD47单克隆抗体晚期恶性肿瘤TJC4
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I-Mab是一家临床阶段生物技术公司，专注于发现和开发免疫肿瘤学创新生物制剂。I-Mab近日宣布，中国国家药品监督管理局（NMPA）已经批准其TJC4的研究性新药申请（IND）。

I-Mab是一家临床阶段生物技术公司，专注于发现和开发免疫肿瘤学创新生物制剂。I-Mab近日宣布，中国国家药品监督管理局（NMPA）已经批准其TJC4的研究性新药申请（IND）。TJC4是一种用于治疗晚期恶性肿瘤的抗CD47单克隆抗体。作为I-Mab创新产品的关键候选药物，TJC4是一种潜在的全球同类最佳的抗CD47单克隆抗体。与其他正在开发的CD47抗体不同，TJC4能够与CD47上的独特表位结合，导致体外血细胞凝集。

I-Mab研发负责人Joan Shen博士表示：“我们很高兴从NMPA获得TJC4的IND，开始在中国进行临床研究。这是我们在美国开展I期研究后的又一重大进展。通过临床前数据，我们相信TJC4具有成为治疗全球癌症患者的巨大潜力”。


原始出处：

http://www.firstwordpharma.com/node/1652814#axzz5tjlSK07B

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    2020-05-28 qidongfanjian

    #CD4#

    0

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    2020-05-20 41514487@qq.com

    #晚期恶性肿瘤#

    0

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    2020-05-07 aids221

    #克隆#

    0