nature biomedical engineering:用于肿瘤检测和图像引导的高分辨率纳米手术探针

2017-03-23 maoguangwei MedSci原创

近日权威杂志nature biomedical engineering在线发表了一篇研究文章,研究人员通过设计一种具有晶体管响应的纳米探针,由于癌组织中的巨大的遗传和组织学差异,以高分辨率检测广泛的恶性肿瘤很有挑战性。文章中报道的具有晶体管响应的纳米探针放大了肿瘤的荧光信号,产生了一个空间分辨率小于1mm的信号。研究人员通过在肿瘤大鼠上进行实时肿瘤 - 酸中毒指导检测和隐匿性结节手术,显着延长了小

近日权威杂志nature biomedical engineering在线发表了一篇研究文章,研究人员通过设计一种具有晶体管响应的纳米探针,由于癌组织中的巨大的遗传和组织学差异,以高分辨率检测广泛的恶性肿瘤很有挑战性。

文章中报道的具有晶体管响应的纳米探针放大了肿瘤的荧光信号,产生了一个空间分辨率小于1mm的信号。

研究人员通过在肿瘤大鼠上进行实时肿瘤 - 酸中毒指导检测和隐匿性结节手术,显着延长了小鼠的生存能力。

该纳米探针有望提高癌症检测,监测和治疗的准确性。

原始出处Zhao, T., et al. (2016). "A transistor-like pH nanoprobe for tumour detection and image-guided surgery." Nature Biomedical Engineering 1: 0006. http://www.nature.com/articles/s41551-016-0006

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    2018-03-06 jeanqiuqiu
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    2017-05-21 spoonycyy
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createdName=spoonycyy, createdTime=Sun May 21 09:01:00 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028435, encodeId=2a89202843516, content=<a href='/topic/show?id=a558829e98a' target=_blank style='color:#2F92EE;'>#肿瘤检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82979, encryptionId=a558829e98a, topicName=肿瘤检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2bcd469, createdName=fengting3, createdTime=Thu Jun 29 15:01:00 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1785400, encodeId=bdbe1e854009a, content=<a href='/topic/show?id=db0e6e8835' target=_blank style='color:#2F92EE;'>#engineering#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6788, 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topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sat Dec 16 12:01:00 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917400, encodeId=3939191e400b6, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Nov 22 22:01:00 CST 2017, time=2017-11-22, status=1, ipAttribution=)]
  5. 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topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sat Dec 16 12:01:00 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917400, encodeId=3939191e400b6, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Nov 22 22:01:00 CST 2017, time=2017-11-22, status=1, ipAttribution=)]
    2018-02-17 lsndxfj
  6. 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  7. 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topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sat Dec 16 12:01:00 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917400, encodeId=3939191e400b6, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Nov 22 22:01:00 CST 2017, time=2017-11-22, status=1, ipAttribution=)]
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  9. 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    2017-12-16 liye789132251
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    2017-11-22 sunylz

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