Neurology:社区运动对于神经肌肉疾病是可行的并且可改善有氧能力

2019-03-10 xing.T 网络

由此可见,在CMT和IBM人群中,社区健身房进行12周的有氧训练是可行的,安全的,并且改善了患者的有氧能力。证据分类本研究提供了II类证据,对于CMT 1A型和IBM型患者,有氧训练计划可增加其有氧能力。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,这项2期试验的目的是确定社区为基础的有氧运动训练对2种更常见的神经肌肉疾病患者的可行性和效果,这两种疾病为Charcot-Marie-Tooth病1A型(CMT)和包涵体肌炎(IBM)。

研究人员采用随机单盲交叉试验设计比较了使用重组运动自行车与对照期相比的12周有氧训练计划。每周在参加者当地的社区健身房进行3次培训。训练有素的健身房工作人员和研究物理治疗师提供支持。分别对2个疾病组进行分析。主要结局指标是在最大运动试验期间的峰值氧摄取(VO2峰值),次要指标为肌肉力量、功能和患者报告的指标。

来自23名CMT患者和17名IBM患者的数据被纳入分析。两个疾病组均具有高水平的参与度,并且可以改善VO2峰值,CMT参与者具有中等效应(Cohen d=0.53),IBM组具有较强效应(Cohen d=1.72)。次要结局指标未观察到重大变化。定期随访显示,参与者强调了体育教师和研究物理治疗师在克服参与挑战方面的支持。

由此可见,在CMT和IBM人群中,社区健身房进行12周的有氧训练是可行的,安全的,并且改善了患者的有氧能力。证据分类本研究提供了II类证据,对于CMT 1A型和IBM型患者,有氧训练计划可增加其有氧能力。

原始出处:

Amanda Wallace,et al.Community exercise is feasible for neuromuscular diseases and can improve aerobic capacity.Neurology.2019.https://doi.org/10.1212/WNL.0000000000007265

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    2019-08-02 yinhl1978
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