结直肠癌候选药物RCC-33将小鼠肿瘤体积降低了27%

2021-02-04 Allan MedSci原创

中期结果显示,与对照小鼠相比,暴露于RCC-33的小鼠的肿瘤体积减少了27%。

结直肠癌,又称为大肠癌,为源自结肠或直肠(为大肠的一部分)的癌症。因为细胞不正常的生长,可能侵犯或转移至身体其他部。症状可能包括粪便中带血、排便习惯改变、体重减轻、以及疲倦感。

制药公司Cannabics今天宣布,该公司正在进行的体内研究已获得中期结果,该研究评估了其候选药物RCC-33治疗结直肠癌的潜力。中期结果显示,与对照小鼠相比,暴露于RCC-33的小鼠的肿瘤体积减少了27%。两组均接种结直肠癌细胞,在第5天开始腹膜内(IP)注射RCC-33。在治疗的5天后,即可观察到两组小鼠肿瘤体积之间的差异;治疗12天后,RCC-33组小鼠的肿瘤体积减少了27%(p= 0.022)。研究正在进行中。

Cannabics总裁兼首席运营官Gabriel Yariv说:“结直肠癌是全球第三大常见的癌症。目前接受治疗患者中有67%可以存活5年或更长时间。我们的目标是进一步提高患者的生存时间”。

 

原始出处:

https://www.firstwordpharma.com/node/1797575?tsid=4

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    2021-07-09 isabellayj
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    2021-02-05 carrotlyl

    好消息

    0

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