BMJ:先天性弓形虫病——病例报道

2016-10-02 MedSci MedSci原创

女性患者,19岁,儿童时期就已存在视力低下的症状。双侧眼底显示,黄斑区有单个较大的椭圆形病变,脉络膜血管较为突出,有色素线,形成典型的货车车轮疤痕(图1⇓)。病人没有抽搐或智力迟钝的病史。CT扫描未发现大脑存在异常。脉络膜视网膜炎是先天性弓形虫病最常见的临床表现(80%)。病变通常会累及黄斑(46%)。大部分先天性弓形虫病患者处于亚临床状态,其发现也是在生活中偶然发现或视力较差接受检查时发现。原始

女性患者,19岁,儿童时期就已存在视力低下的症状。双侧眼底显示,黄斑区有单个较大的椭圆形病变,脉络膜血管较为突出,有色素线,形成典型的货车车轮疤痕(图1⇓)。病人没有抽搐或智力迟钝的病史。CT扫描未发现大脑存在异常。


脉络膜视网膜炎是先天性弓形虫病最常见的临床表现(80%)。病变通常会累及黄斑(46%)。大部分先天性弓形虫病患者处于亚临床状态,其发现也是在生活中偶然发现或视力较差接受检查时发现。

补充:先天性弓形体病多为无症状的隐匿型,严重感染或免疫功能缺陷时发病。弓形体眼病主要表现为视网膜脉络膜炎。临床以中心性渗出性视网膜炎为常见。由于破坏性炎症及变态反应关系,自愈倾向与反复发作,常可留下永久性瘢痕,严重地影响视力,并可发生视网膜剥离、白内障、斜视和眼球震颤,继发性乳头萎缩,青光眼等病变,甚至最终失明。

原始出处:

Koushik Tripathy, Yog Raj Sharma. Congenital toxoplasmosis. BMJ 2016; 354 doi: http://dx.doi.org/10.1136/bmj.i5028.
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    2017-03-24 gaoxiaoe
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    2016-10-13 1e10c84am36(暂无匿称)

    文章真好,喜欢阅读

    0

  4. 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target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456981, encodeId=520a1456981ed, content=<a href='/topic/show?id=4ade4985643' target=_blank style='color:#2F92EE;'>#弓形虫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49856, encryptionId=4ade4985643, topicName=弓形虫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7095824508, createdName=zhangj7110, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=139572, encodeId=b7751395e268, content=视网膜脉络膜炎很难治愈!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Oct 03 16:20:25 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
    2016-10-13 1e10c84am36(暂无匿称)

    文章真好,喜欢阅读

    0

  5. 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target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456981, encodeId=520a1456981ed, content=<a href='/topic/show?id=4ade4985643' target=_blank style='color:#2F92EE;'>#弓形虫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49856, encryptionId=4ade4985643, topicName=弓形虫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7095824508, createdName=zhangj7110, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=139572, encodeId=b7751395e268, content=视网膜脉络膜炎很难治愈!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Oct 03 16:20:25 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
    2016-10-11 1e10c84am36(暂无匿称)

    好文章,长见识

    0

  6. 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target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456981, encodeId=520a1456981ed, content=<a href='/topic/show?id=4ade4985643' target=_blank style='color:#2F92EE;'>#弓形虫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49856, encryptionId=4ade4985643, topicName=弓形虫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7095824508, createdName=zhangj7110, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=139572, encodeId=b7751395e268, content=视网膜脉络膜炎很难治愈!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Oct 03 16:20:25 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
    2016-10-07 吴教授

    学习了,学习了。

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=139572, encodeId=b7751395e268, content=视网膜脉络膜炎很难治愈!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Oct 03 16:20:25 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
    2016-10-04 明月清辉

    弓形虫,可怕。

    0

  8. 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    2016-10-04 huirong
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target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456981, encodeId=520a1456981ed, content=<a href='/topic/show?id=4ade4985643' target=_blank style='color:#2F92EE;'>#弓形虫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49856, encryptionId=4ade4985643, topicName=弓形虫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7095824508, createdName=zhangj7110, createdTime=Tue Oct 04 05:04:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=139572, encodeId=b7751395e268, content=视网膜脉络膜炎很难治愈!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Oct 03 16:20:25 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
    2016-10-03 1e0d99ddm02(暂无匿称)

    视网膜脉络膜炎很难治愈!

    0