BRAIN BEHAV IMMUN:母亲童年经济情况影响后代健康

2017-09-25 海北 MedSci原创

已有的研究表明,经济困难对健康的影响是可以跨代遗传的,这些信息中有一部分被认为是在妊娠期遗传给后代的。但是至今为止,该假设还没有在当代美国样本中进行测试。此外,经济困难跨代遗传的机制也没有得到解释。

已有的研究表明,经济困难对健康的影响是可以跨代遗传的,这些信息中有一部分被认为是在妊娠期遗传给后代的。但是至今为止,该假设还没有在当代美国样本中进行测试。此外,经济困难跨代遗传的机制也没有得到解释。

为此,来自美国西北大学的研究人员进行了一项测试,该测试的目的有两个:第一,测试在儿童期间遭受经济困难的妇女是否和较高的不良出生现象相关;第二,评估炎症,社会心理,生活方式和产科特征对这种现象的贡献。该项前瞻性研究一共招募了744名单身妊娠女性(59.1%白人; 16.3%黑人; 18.7%拉丁裔; 5.9%其他)。研究人员通过志愿者的自我报告来衡量其童年经济困难情况。对出生结果的记录包括妊娠期的长度,早产的发生率,出生体重,是否胎龄较小,住院时间,以及特殊护理时间。

研究结果显示,母亲童年经济困难和多个不利的出生结果独立相关,在针对人口统计学,母亲教育和产科混杂因素进行调整后依然成立。在经济上处于不利条件的妇女,妊娠期较短,早产儿率较高。她们的婴儿出生体重较低,胎龄较小,住院时间较长,并且需要更多的特殊护理。调解分析表明,这些联系通过多种途径产生,炎症,教育,肥胖和产科并发症的作用被强调了。

因此,这表明儿童期的经济困难会使得女性更容易遭受不利的出生后果。


原始出处:

Gregory E.Miller et al. Mothers’ childhood hardship forecasts adverse pregnancy outcomes: Role of inflammatory, lifestyle, and psychosocial pathways. Brain, Behavior, and Immunity, 2017; DOI: https://doi.org/10.1016/j.bbi.2017.04.018


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    2017-09-27 qjddjq
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    2017-09-26 187清风

    单纯是母亲儿时经济差还是现在也是?

    0

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    2017-09-26 cherry bomb

    学习了谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1947858, encodeId=55dc194e85879, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sun Sep 02 12:26:00 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041884, encodeId=ff0c20418849a, content=<a href='/topic/show?id=e4413904e9d' target=_blank style='color:#2F92EE;'>#后代健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39047, encryptionId=e4413904e9d, topicName=后代健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sun Jan 28 16:26:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1521879, encodeId=4a6415218e94c, content=<a href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Wed Sep 27 13:26:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=247820, encodeId=4b7d24e82072, content=单纯是母亲儿时经济差还是现在也是?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb571956164, createdName=187清风, createdTime=Tue Sep 26 07:54:33 CST 2017, time=2017-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=247767, encodeId=a3d024e767f1, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4Cr8ibeWnmTmmC1lthicNVicicXTX7Mn9OEib5S1eHg4jhM9usWmW2NBVm6NaJurhgeMl3UJ1gujuaQuIX7icVSa8F4JoFPCfib0Prsk/0, createdBy=b5bb2069360, createdName=cherry bomb, createdTime=Tue Sep 26 06:49:14 CST 2017, time=2017-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=247676, encodeId=23d524e676ee, content=心理作用是会对遗传健康产生影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=27762113155, createdName=小铭的皮普, createdTime=Mon Sep 25 22:44:21 CST 2017, time=2017-09-25, status=1, ipAttribution=)]
    2017-09-25 小铭的皮普

    心理作用是会对遗传健康产生影响

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