BMC Public Health:咖啡有助于降低慢性肝病发生风险

2021-06-27 MedSci原创 MedSci原创

慢性肝病(CLD)已成为全球健康问题。据数据显示,1990年至2017年全球因CLD致死的人数从89.9万(占总数的1.9%)增加到132万(占总数的2.4%)。

慢性肝病(CLD)已成为全球健康问题。据数据显示,1990年至2017年全球因CLD致死的人数从89.9万(占总数的1.9%)增加到132万(占总数的2.4%)。在同一时期,因CLD致残疾的人数从3050万增加到4140万。在中低收入国家,CLD的负担最高,而这些国家的治疗方案也很有限。

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先前有研究显示,饮用咖啡可降低CLD发病率。但不同的咖啡类型对CLD的影响却知之甚少。近日,发表在BMC Public Health杂志的一项研究调查了饮用咖啡包与慢性肝病的关联,包括脱咖啡因咖啡、速溶咖啡和研磨咖啡。

该研究分析了来自 UK Biobank 数据库的494585名参与者数据,年龄为40-69岁。所有参与者都进行了体检,包括病史和生活方式,并提供了尿液和血液样本。通过调查问卷确定了参与者咖啡消费量。

结果发现,384818饮用了磨碎或速溶咖啡因或不含咖啡因的咖啡,而109767的人不喝任何类型的咖啡。中位随访 10.7 年期间,有3600名参与者发生慢性肝病,其中301例死亡,有5439名发生慢性肝病或脂肪变性,184名患有肝癌。

所有类型咖啡与慢性肝病、慢性肝病或脂肪变性、慢性肝病导致的死亡和肝癌的关联

与不喝咖啡的人相比,喝咖啡的人患慢性肝病,脂肪肝和慢性肝病死亡率都有所降低,分别为21%20%49%,且饮用咖啡次数越多效果越明显。但是每天约三到四杯益处达到顶峰,进一步增加并没有带来额外的益处。

综上,所有类型的咖啡(包括不含咖啡因的咖啡)对 CLD 结果的保护作用。鉴于缺乏有效的 CLD 预防和治疗策略,尤其是在 CLD 负担最重的中低收入国家,这些发现意义重大。

原始出处

Oliver J. Kennedy.et al.All coffee types decrease the risk of adverse clinical outcomes in chronic liver disease: a UK Biobank study.BMC Public Health .https://doi.org/10.1186/s12889-021-10991-7

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    2022-07-22 爱太阳的蜗牛🐌

    值得学习

    0

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    2022-05-29 shizhenshan
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    2021-06-27 呀丫丫

    涨知识😶

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1233946, encodeId=f1e8123394619, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a4a5534697, createdName=爱太阳的蜗牛🐌, createdTime=Fri Jul 22 00:30:12 CST 2022, time=2022-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975098, encodeId=f59319e5098c8, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Nov 13 08:57:16 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861445, encodeId=a2831861445f4, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Sun May 29 00:57:16 CST 2022, time=2022-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621906, encodeId=e10716219068b, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Tue Jun 29 10:57:16 CST 2021, time=2021-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977405, encodeId=d61b9e740537, content=涨知识😶, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200729/ebb1ca1c491b4b00b3c28eaa1e8eea0d/9561d33e50d945068f349ff13de691c0.jpg, createdBy=7d935403389, createdName=呀丫丫, createdTime=Sun Jun 27 20:53:20 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977403, encodeId=9ec29e74033c, content=学习啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/0e8142bbb4a04eb78e71a2d739e0aac0/4a0cee7114594824a0a9903ac1495565.jpg, createdBy=c9e91732173, createdName=Angela Yu, createdTime=Sun Jun 27 20:38:14 CST 2021, time=2021-06-27, status=1, ipAttribution=)]
    2021-06-27 Angela Yu

    学习啦

    0

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