AIBD 2016:存在IBS症状的IBD女性患者更易发生慢性疲劳

2016-12-11 MedSci MedSci原创

据AIBD 2016上展示的一项新娥研究表明,炎症性肠病同时伴有肠易激综合征的患者,尤其是女性,或可增加慢性疲劳的风险。为了探究IBD患者中IBS症状与慢性疲劳之间的关联,并确定影响慢性疲劳患者的预后因素,研究人员评估了参与20年IBSEN研究的470例IBD患者,该研究已在2014年完成。记录患者的症状,并完成了临床检查、实验室检查、IBS症状评分和慢性疲劳问卷调查。在344名钙卫蛋白数据可获得

据AIBD 2016上展示的一项新娥研究表明,炎症性肠病同时伴有肠易激综合征的患者,尤其是女性,或可增加慢性疲劳的风险。

为了探究IBD患者中IBS症状与慢性疲劳之间的关联,并确定影响慢性疲劳患者的预后因素,研究人员评估了参与20年IBSEN研究的470例IBD患者,该研究已在2014年完成。

记录患者的症状,并完成了临床检查、实验室检查、IBS症状评分和慢性疲劳问卷调查。在344名钙卫蛋白数据可获得的患者中,264名(77%)患者处于临床缓解期(平均年龄55岁)。

处于缓解期中的患者,182名有溃疡性结肠炎(UC),82名有克罗恩病,平均病程为19年。此外,68名(26%)有肠易激综合征的症状,这其中又有25名(37%)有慢性疲劳(33%,UC; 44%,克罗恩病)。

研究人员发现,存在IBS症状的患者中,女性明显比男性更容易患上慢性疲劳(44% VS. 33%;P =0. 03)。

相反,仅15%无IBS症状的患者有慢性疲劳,明显低于存在IBS症状的患者(P<0.0001)。

结合IBS和慢性疲劳作为因变量,性别和诊断作为自变量,经Logistic回归分析表明,女性是慢性疲劳的显著预测因子(OR= 5.3;95% CI,1.8-15.9)。

研究人员认为,其研究结果表明,处于缓解期,但是存在IBS症状的IBD患者其慢性疲劳的发病率较高,且远高于匹配年龄组的一般人群。

原始出处:

Adam Leitenberger. IBD patients with IBS may have higher risk for chronic fatigue. Healio, December 10, 2016.


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    2016-12-13 tamgche
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    2016-12-13 bnurmamat
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    2016-12-13 柳叶一刀
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    2016-12-12 thlabcde

    是真的!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2033502, encodeId=9bb02033502fa, content=<a href='/topic/show?id=446044648ad' target=_blank style='color:#2F92EE;'>#女性患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44648, encryptionId=446044648ad, topicName=女性患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Oct 13 20:30:00 CST 2017, time=2017-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260840, encodeId=7fb9126084033, content=<a href='/topic/show?id=493ee0559a7' target=_blank style='color:#2F92EE;'>#疲劳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70559, encryptionId=493ee0559a7, topicName=疲劳)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Tue Dec 13 09:30:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263429, encodeId=44a3126342999, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Tue Dec 13 09:30:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307652, encodeId=e2cb130e652bd, content=<a href='/topic/show?id=04ab931993' target=_blank style='color:#2F92EE;'>#IBS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9319, encryptionId=04ab931993, topicName=IBS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Tue Dec 13 09:30:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162080, encodeId=dc2e1620809d, content=是真的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Dec 12 07:01:55 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162006, encodeId=6296162006cc, content=不错,继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Sun Dec 11 19:43:49 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 知难而进

    不错,继续关注

    0

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