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Diabetes Care:阻塞性睡眠呼吸暂停影响胰岛素敏感性和分泌

2012-08-29 高晓方译 医学论坛网

阻塞性睡眠呼吸暂停胰岛素敏感性胰岛素抵抗
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　　美国学者的一项研究表明，在青年消瘦男性中，阻塞性睡眠呼吸暂停（OSA）与胰岛素抵抗和胰岛素分泌代偿性升高具有相关性。论文于2012年8月21日在线发表于《糖尿病护理》（Diabetes Care）杂志。 　　此项前瞻性研究共纳入52例接受多导睡眠图和晨起口服糖耐量试验的消瘦健康男性。依据种族糖尿病风险和糖尿病家族史对受试者进行分层。选取无OSA的20例对照男性和伴OSA的12例男性

　　美国学者的一项研究表明，在青年消瘦男性中，阻塞性睡眠呼吸暂停（OSA）与胰岛素抵抗和胰岛素分泌代偿性升高具有相关性。论文于2012年8月21日在线发表于《糖尿病护理》（Diabetes Care）杂志。

　　此项前瞻性研究共纳入52例接受多导睡眠图和晨起口服糖耐量试验的消瘦健康男性。依据种族糖尿病风险和糖尿病家族史对受试者进行分层。选取无OSA的20例对照男性和伴OSA的12例男性，并就糖耐量指数、胰岛素敏感性和胰岛素分泌进行对比评估。

　　结果显示，伴和未伴OSA的男性在年龄、体质指数（BMI）、种族糖尿病风险、糖尿病家族史和运动水平方面基本相似。两组受试者的收缩压、舒张压和空腹血脂水平均正常。与对照者相比，OSA受试者在摄入糖负荷后胰岛素敏感性降低27%，总体胰岛素分泌升高37%，但血糖水平基本相似。

　　链接：Sushmita Pamidi, MD1⇓,Kristen Wroblewski, MSC2,Josiane Broussard, PHD1, Andrew Day, BSC1, Erin C. Hanlon, PHD1,Varghese Abraham, MD1 and Esra Tasali, MD1 Obstructive Sleep Apnea in Young Lean Men: Impact on insulin sensitivity and secretion. Diabetes Care



    

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    2012-09-21 juliusluan78

    #胰岛素敏感#

    0

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    2013-04-28 ms9608593228839890

    #DIA#

    0

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    2013-04-16 木头人513

    #Diabetes#

    0

  4. 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createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Apr 28 08:28:00 CST 2013, time=2013-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1900995, encodeId=35b01900995df, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Apr 16 19:28:00 CST 2013, time=2013-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1682128, encodeId=3e3f1682128a3, content=<a href='/topic/show?id=d4d031e8074' target=_blank style='color:#2F92EE;'>#分泌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2012-11-06 gwc392

    #分泌#

    0

  5. 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encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2013-04-09 ms5439512287675881

    #BET#

    0

  6. 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createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Apr 28 08:28:00 CST 2013, time=2013-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1900995, encodeId=35b01900995df, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Apr 16 19:28:00 CST 2013, time=2013-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1682128, encodeId=3e3f1682128a3, content=<a href='/topic/show?id=d4d031e8074' target=_blank style='color:#2F92EE;'>#分泌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2013-01-13 zhanfl

    #睡眠呼吸#

    0

  7. 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topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2013-05-28 baoya

    #胰岛#

    0

  8. 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createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Apr 28 08:28:00 CST 2013, time=2013-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1900995, encodeId=35b01900995df, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Apr 16 19:28:00 CST 2013, time=2013-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1682128, encodeId=3e3f1682128a3, content=<a href='/topic/show?id=d4d031e8074' target=_blank style='color:#2F92EE;'>#分泌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2012-10-06 tomyang96

    #阻塞#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1944943, encodeId=278d194494310, content=<a href='/topic/show?id=b2fd838849c' target=_blank style='color:#2F92EE;'>#胰岛素敏感#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83884, encryptionId=b2fd838849c, topicName=胰岛素敏感)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Fri Sep 21 05:28:00 CST 2012, time=2012-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636556, encodeId=313f163655625, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Apr 28 08:28:00 CST 2013, time=2013-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1900995, encodeId=35b01900995df, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Apr 16 19:28:00 CST 2013, time=2013-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1682128, encodeId=3e3f1682128a3, content=<a href='/topic/show?id=d4d031e8074' target=_blank style='color:#2F92EE;'>#分泌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2012-08-31 ms5236388012055669

    #敏感性#

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1944943, encodeId=278d194494310, content=<a href='/topic/show?id=b2fd838849c' target=_blank style='color:#2F92EE;'>#胰岛素敏感#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83884, encryptionId=b2fd838849c, topicName=胰岛素敏感)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Fri Sep 21 05:28:00 CST 2012, time=2012-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636556, encodeId=313f163655625, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Apr 28 08:28:00 CST 2013, time=2013-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1900995, encodeId=35b01900995df, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Apr 16 19:28:00 CST 2013, time=2013-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1682128, encodeId=3e3f1682128a3, content=<a href='/topic/show?id=d4d031e8074' target=_blank style='color:#2F92EE;'>#分泌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31780, encryptionId=d4d031e8074, topicName=分泌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0da227938338, createdName=gwc392, createdTime=Tue Nov 06 09:28:00 CST 2012, time=2012-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759186, encodeId=4a6b1e5918607, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Tue Apr 09 09:28:00 CST 2013, time=2013-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988950, encodeId=7cd219889502d, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Jan 13 16:28:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749367, encodeId=8df31e49367ff, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue May 28 17:28:00 CST 2013, time=2013-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696611, encodeId=1d491696611fe, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sat Oct 06 10:28:00 CST 2012, time=2012-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388280, encodeId=598e138828033, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596415, encodeId=c73e1596415ec, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Fri Aug 31 01:28:00 CST 2012, time=2012-08-31, status=1, ipAttribution=)]
    2012-08-31 119337463

    #呼吸暂停#

    0

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