Sci Rep:在中国男性中,三酸甘油脂和血糖指数与性腺机能减退的相关性要比HOMA-IR的更强

2017-11-29 AlexYang MedSci原创

之前的研究报道了胰岛素抵抗和性腺功能低下症相关。三酸甘油酯和血糖指数(TyG)能够很好的反应胰岛素的敏感性。并且还没有研究调查TyG在男性性腺机能减退的应用。最近,有研究人员探索了是否TyG与男性性腺机能减退相关,并且评估了TyG作为可能的性腺机能减退预测子的能力,并且与HOMA-IR进行了比较。研究总共包括了4299名男性参与者,他们来自中国东部的22个城市。性腺机能减退被定义为总睾丸素水平小于

之前的研究报道了胰岛素抵抗和性腺功能低下症相关。三酸甘油酯和血糖指数(TyG)能够很好地反应胰岛素的敏感性。并且还没有研究调查TyG在男性性腺机能减退的应用。最近,有研究人员探索了是否TyG与男性性腺机能减退相关,并且评估了TyG作为可能的性腺机能减退预测子的能力,并且与HOMA-IR进行了比较。

研究总共包括了4299名男性参与者,他们来自中国东部的22个城市。性腺机能减退被定义为总睾丸素水平小于11.3nmol/L。研究发现,695名具有性腺机能减退的男性参与者(16.2%)具有显著更高的TyG指数。性腺机能减退的流行度随着TyG四分位的增加而呈现阶梯式增加(P<0.01)。在调整了年龄、抽烟状态、高血压和超重/肥胖参数后,研究人员发现TyG与性激素和性腺机能减退呈现负相关关系(所有的P-trend<0.01)。TyG的最低四分位与最高四分位相比,调整后的风险比为6.1(95% CI 4.51, 8.25, P<0.001)。在ROC曲线分析中,研究人员在TyG中发现了要比HOMA-IR(0.68, 95% CI 0.66,0.70)更大的曲线下面积(0.71, 95% CI 0.69,0.73)。因此,在中国男性中,TyG与更高的性腺机能减退流行度显著相关。并且,TyG要比性腺机能减退具有更高的预测能力。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1837394, encodeId=3e75183e3946f, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sat Jan 06 20:33:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265442, encodeId=460b26544281, content=学了........, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Wed Nov 29 22:54:29 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265439, encodeId=926f2654393e, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Nov 29 22:53:35 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265420, encodeId=8224265420f7, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Nov 29 21:36:57 CST 2017, time=2017-11-29, status=1, ipAttribution=)]
    2017-11-29 135****7952平儿

    学了........

    0

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    2017-11-29 changjiu

    学习一下谢谢

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1837394, encodeId=3e75183e3946f, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sat Jan 06 20:33:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265442, encodeId=460b26544281, content=学了........, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Wed Nov 29 22:54:29 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265439, encodeId=926f2654393e, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Nov 29 22:53:35 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265420, encodeId=8224265420f7, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Nov 29 21:36:57 CST 2017, time=2017-11-29, status=1, ipAttribution=)]
    2017-11-29 1e1b8538m79(暂无匿称)

    不错的文章值得推荐

    0

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