BJD:治疗秃顶新方法,向头部注射自己血液?

2013-05-10 koo 生物360

注射“富血小板血浆(PRP)”可有效减缓人们面部和手部衰老,一项最新测试表明,该方法也能使秃顶男性重新长出浓密头发。研究人员称,抽取秃顶男性体内血液的富血小板血浆,注射在头皮之下刺激新干细胞,从而促进头发再生,这一过程被称为“吸血鬼疗法”。来自国际毛发研究基金会、意大利布雷沙大学和以色列希伯来大学研究中心的科学家们共同完成了这项测试,测试者是45位男性脱发者,一部分人注射富血小板血浆;一部分人涂抹

注射“富血小板血浆(PRP)”可有效减缓人们面部和手部衰老,一项最新测试表明,该方法也能使秃顶男性重新长出浓密头发。
研究人员称,抽取秃顶男性体内血液的富血小板血浆,注射在头皮之下刺激新干细胞,从而促进头发再生,这一过程被称为“吸血鬼疗法”。
来自国际毛发研究基金会、意大利布雷沙大学和以色列希伯来大学研究中心的科学家们共同完成了这项测试,测试者是45位男性脱发者,一部分人注射富血小板血浆;一部分人涂抹类固醇乳霜;剩余的人则使用安慰剂。
这些不同的治疗方法以每个月作为治疗周期,研究人员测试秃顶处新生头发的数量,结果显示富血小板血浆注射之后生长头发的效果远超过其它两种方法。目前,这项研究的详细资料发表在《英国皮肤医学杂志》上,科学家希望能够研制一种乳霜,从而不必使用注射的方式。
研究人员表示,这种最新治疗技术将为男性秃顶患者带来福音,我们认为它能够帮助男性雄激素源性脱发患者重生头发,这是除手术之外最佳的治疗方案。

Background
Alopecia areata (AA) is a common auto-immune condition, causing inflammation-induced hair loss. This disease has very limited treatment possibilities, and no treatment is either curative or preventive. Platelet-rich plasma (PRP) has emerged as a new treatment modality in dermatology, and preliminary evidence has suggested it might have a beneficial role in hair growth.
Objectives
To evaluate the efficacy and safety of PRP for the treatment of AA in a randomized, double-blinded, placebo and active-controlled, half-head, parallel group study.
Methods
Forty five AA patients were randomized to receive intralesional injections of PRP, triamcinolone acetonide (TrA) or placebo on one half of their scalp. The other half was not treated. A total of three treatments were given for each patient, with an interval of one month from each other. The endpoints were hair regrowth, hair dystrophy as measured by dermoscopy, burning/itching sensation and cell prolifertation as measured by Ki-67 evaluation. Patients were followed for 1 year.
Results
PRP was found to significantly increase hair regrowth and decrease hair dystrophy and burning/itching sensation when compared with TrA or placebo, and Ki-67 levels, which served as markers for cell proliferation, were significantly higher. No side effects were noted during treatment.
Conclusions
This pilot study, which is the first to investigate the effects of PRP on AA, suggests that PRP may serve as a safe and effective treatment option in AA, and calls for more extensive controlled studies with this method.

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