期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Peripheral nerve injury is a serious health problem and repairing long nerve deficits remains a clinical challenge nowadays. Nerve guidance conduit (N......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Alzheimer's disease (AD) is a progressive neurodegenerative disease with high prevalence rate among the elderly population. A large number of clinical......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Defective amyloid-beta (A beta) clearance from the brain is a major contributing factor to the pathophysiology of Alzheimer's disease (AD). A beta cle......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Circumstantial evidence points to a pathological role of alpha-synuclein (aSyn; gene symbol SNCA), conferred by aSyn misfolding and aggregation, in Pa......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Cancer stem cells (CSCs) contribute to radioresistance in medulloblastoma. Thus, identification of key regulators of medulloblastoma stemness is criti......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Age at onset of amyotrophic lateral sclerosis (ALS) is highly variable (eg, 27-74 years in carriers of the G(4)C(2)-expansion in C9orf72). It might be......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
The pathogenic mechanisms underlying the development of Alzheimer's disease (AD) remain elusive and to date there are no effective prevention or treat......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Down syndrome (DS) is the leading genetic cause of intellectual disability and causes early-onset dementia and cerebellar hypoplasia. The prevalence o......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Introduction Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer's disease (AD). Besides direct neur......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Transcribed nucleotide repeat expansions form detectable RNA foci in patient cells that contribute to disease pathogenesis. The most widely used metho......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Mutations in the DNAJB6 gene have been identified as rare causes of myofibrillar myopathies. However, the underlying pathophysiologica mechanisms rema......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer's disease (AD) and related tauopathies. Regional......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1)
Peripheral biomarkers indicative of brain pathology are critically needed for early detection of Parkinson's disease (PD). In this study, using NanoSt......
期刊： ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2020; 8 (1)
Adult medulloblastomas are clinically and molecularly understudied due to their rarity. We performed molecular grouping, targeted sequencing, and TERT......
