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Gender-specific impact of cognitive impairment on all-cause mortality in older persons: A meta-analysis

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 165 ()

Background: Gender-specific impact of cognitive impairment on survival in the general population remains controversial. The objective of this meta-ana......

JIF:3.746

NR4A1 promotes oxidative stresses after myocardial ischemia reperfusion injury in aged mice

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 162 ()

Myocardial infarction (MI) is a serious disease which is responsible for major death in the elderly. Myocardial oxidative stress contributes to pathop......

JIF:3.746

The effects of raloxifene on endothelial function and Inflammation in Postmenopausal women: A Meta-analysis of randomized controlled trials

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 159 ()

Background and aim: Raloxifene treatment has been reported to be associated with cardiovascular benefits if prescribed to women during the postmenopau......

JIF:3.746

Brainstem auditory evoked potential in cognitive impairment in patients with type 2 diabetes mellitus

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 159 ()

Purpose: Type 2 diabetes mellitus (T2DM) can cause mild cognitive impairment (MCI) which threatens the health of patients. So the diagnosis of MCI is ......

JIF:3.746

The leaves of Scutellaria baicalensis Georgi attenuate brain aging in D-galactose-induced rats via regulating glutamate metabolism and Nrf2 signaling pathway

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 170 ()

The present study aimed to evaluate the anti-aging effect of the leaves of Scutellaria baicalensis Georgi (LSBG) and investigate its mechanisms. For t......

JIF:3.746

Changes in the tight junctions of the testis during aging: Role of the p38 MAPK/MMP9 pathway and autophagy in Sertoli cells

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 161 ()

Impaired tight junction (TJ) function and autophagy and the activated p38 mitogen-activated protein kinase (MAPK)/matrix metalloproteinase 9 (MMP9) pa......

JIF:3.746

Parkin-mediated mitophagy protects against TNF-?-induced stress in bone marrow mesenchymal stem cells

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 164 ()

Bone marrow mesenchymal stem cells (BMSCs) have been investigated as cellular therapeutics for intervertebral disc degeneration. However, transplanted......

JIF:3.746

Intrinsic capacity and 10-year mortality: Findings from a cohort of older people

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 167 ()

Background and objectives: Longitudinal data with regard to the association between intrinsic capacity (IC) and mortality is required for prevention e......

JIF:3.746

Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 169 ()

The incidence of aging-related cognitive decline is increasing with population aging. It is urgent to explore ways to ameliorate aging-related cogniti......

JIF:3.746

Comprehensive 16S rRNA sequencing based microbiomes and H-1 NMR based metabolomics reveal the relationships of aging and constipation

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 166 ()

Aging is a complex physiological process associated with degenerative disorders of metabolism and intestinal flora. Constipation is an age-dependent g......

JIF:3.746

Platelet protects angiotensin II-driven abdominal aortic aneurysm formation through inhibition of inflammation

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 159 ()

Background: Inflammation is the primary cause of abdominal aortic aneurysm (AAA) formation and development. It has been reported that platelets protec......

JIF:3.746

Immunosenescence evaluation of peripheral blood lymphocyte subsets in 957 healthy adults from 20 to 95 years old

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 157 ()

Immunosenescence is characterized by an age-related decline in immune system function. Major efforts have been made to identify changes in peripheral ......

JIF:3.746

DHPW1 attenuation of UVB-induced skin photodamage in human immortalized keratinocytes

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 166 ()

Ultraviolet radiation (UVB) can result in photodamage to the skin and can seriously threaten health, particularly in the elderly. Oxidative stress and......

JIF:3.746

Newly discovered molecules associated with trimetazidine on improvement of skeletal muscle function in aging: evidence from myoblasts and mice

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 161 ()

Poor muscle function is increasingly obvious with aging and needs effective and safe medicine for treatment. Trimetazidine (TMZ) has potential benefit......

JIF:3.746

Inflammaging: The ground for sarcopenia?

期刊: EXPERIMENTAL GERONTOLOGY, 2022; 168 ()

Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the elderly population, contributing to increased costs and hospitali......

JIF:3.746

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