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Clinical applications of extracellular vesicle long RNAs

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2020; 57 (8)

Extracellular vesicles (EVs), primarily exosomes and microvesicles, are critical intercellular mediators of communication. Over the past decade, impro......

The COVID-19 pandemic

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2020; 57 (6)

In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan, Hubei Province, China. Pneumonia cases were epidemiologically link......

Novel perspectives in fetal biomarker implementation for the noninvasive prenatal testing

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2019; 56 (6)

Noninvasive prenatal testing (NIPT) utilizes cell-free fetal DNA (cffDNA) present in maternal peripheral blood to detect chromosomal abnormalities. Th......

JIF:4.82

Linking lncRNAs to regulation, pathogenesis, and diagnosis of pulmonary hypertension

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 0; ()

Pulmonary hypertension (PH) is a syndrome characterized by a persistent increase in pulmonary vascular resistance. Due to the lack of specificity in c......

Exploring the role of programmed cell death protein 1 and its ligand 1 in eye diseases

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2019; 56 (1)

Programmed death receptor-1 (PD-1) and its ligand, PD-L1, as negative co-stimulatory molecules, are indispensable for regulating both physiological an......

JIF:4.82

Non-antibiotic therapy for Clostridioides difficile infection: A review

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2019; 56 (7)

Clostridioides difficile infection (CDI) is a common infectious disease that is mainly caused by antibiotics. Antibiotic therapy is still the dominant......

JIF:4.82

FDA-approved drugs that interfere with laboratory tests: A systematic search of US drug labels

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2017; 54 (1)

Drug-related laboratory test interference or drug/laboratory test interactions (DLTI) are a major source of laboratory errors. DLTI is of concern with......

JIF:6.48

Capillary blood for point-of-care testing

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2017; 54 (5)

Clinically, blood sample analysis has been widely used for health monitoring. In hospitals, arterial and venous blood are utilized to detect various d......

JIF:6.48

The molecular structure and biological functions of RNA methylation, with special emphasis on the roles of RNA methylation in autoimmune diseases

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2022; 59 (3)

Autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic vasculitis are caused by the body's immune res......

JIF:5.75

Clinical utility of procalcitonin and its association with pathogenic microorganisms

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2022; 59 (2)

In this review, we summarize the relationship of PCT with pathogens, evaluate the clinical utility of PCT in the diagnosis of clinical diseases, condi......

JIF:5.75

Design, optimization, and application of multiplex rRT-PCR in the detection of respiratory viruses

期刊: CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2022; 59 (8)

Viral respiratory infections are common and serious diseases. Because there is no effective treatment method or vaccine for respiratory tract infectio......

JIF:5.75

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