Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs

Tailhades, J; Takizawa, H; Gait, MJ; Wellings, DA; Wade, JD; Aoki, Y; Shabanpoor, F

Shabanpoor, F (reprint author), Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Parkville, Vic, Australia.; Shabanpoor, F (reprint author), Univ Melbourne, Sch Chem, Parkville, Vic, Australia.

FRONTIERS IN CHEMISTRY, 2017; 5 ( ):

Abstract

Antisense oligonucleotide (ASO)-based drug development is gaining significant momentum following the recent FDA approval of Eteplirsen (an ASO based o......

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