Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia

Stein, EM; DiNardo, CD; Pollyea, DA; Fathi, AT; Roboz, GJ; Altman, JK; Stone, RM; DeAngelo, DJ; Levine, RL; Flinn, IW; Kantarjian, HM; Collins, R; Patel, MR; Frankel, AE; Stein, A; Sekeres, MA; Swords, RT; Medeiros, BC; Willekens, C; Vyas, P; Tosolin

Stein, EM (reprint author), Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, 1275 York Ave, New York, NY 10065 USA.

BLOOD, 2017; 130 (6): 722

Abstract

Recurrent mutations in isocitrate dehydrogenase 2 (IDH2) occur in similar to 12% of patients with acute myeloid leukemia (AML). Mutated IDH2 proteins ......

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