Circle-Seq reveals genomic and disease-specific hallmarks in urinary cell-free extrachromosomal circular DNAs

Lv, W; Pan, XG; Han, P; Wang, ZY; Feng, WJ; Xing, X; Wang, QQ; Qu, KL; Zeng, YC; Zhang, CL; Xu, Z; Li, Y; Zheng, TY; Lin, L; Liu, CX; Liu, XM; Li, HB; Henriksen, RA; Bolund, L; Lin, L; Jin, X; Yang, HM; Zhang, XQ; Yin, TL; Regenberg, B; He, F; Luo, YL

Luo, YL (通讯作者)，Chinese Acad Sci, IBMC BGI Ctr, Canc Hosp, Univ Chinese Acad Sci,Zhejiang Canc Hosp,Inst Bas, Hangzhou 310022, Zhejiang, Peoples R China.;He, F (通讯作者)，Huazhong Univ Sci & Technol, Tongji Hosp, Dept Nephrol, Tongji Med Coll, Wuhan, Peoples R China.

CLINICAL AND TRANSLATIONAL MEDICINE, 2022; 12 (4):

Abstract

Background Extrachromosomal circular deoxyribonucleic acid (eccDNA) is evolving as a valuable biomarker, while little is known about its presence in u......

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