Alzheimer’s & Dementia:社会经济地位低的区域痴呆症漏诊率、延误诊断率高

2022-03-28 MedSci原创 MedSci原创

在社会经济地位低的城市可能存在大量的痴呆症漏诊。

几项研究表明,痴呆症的诊断不足造成大量患者面临着未得到适当的痴呆症护理的风险。尽管目前还没有药物治疗方案来积极预防或阻止阿尔茨海默氏病(AD)等神经退行性疾病引起的痴呆的进展,但痴呆症的早期诊断非常重要。已知的痴呆症危险因素包括心血管疾病以及社会经济地位(SES),包括教育、收入、职业和童年SES。社会经济因素可能影响诊断的时间;然而,关于这方面的文献很少。一个地理区域的贫困程度,通常称为邻里社会经济地位(neighborhood socioeconomic status, nSES),是影响一般健康和福祉的一个风险因素。然而,关于nSES与痴呆风险之间的关系的研究结果并不一致。

Ellen Holm等在Alheimer’s & Dementia杂志发表题为Frequency of missed or delayed diagnosis in dementia is associated with neighborhood socioeconomic status研究文章,调查nSES与痴呆症漏诊或延迟诊断之间的关系。

在社会经济地位较低的地区,对痴呆症的检测不足可能会干扰有关社会经济地位和痴呆症之间关联的研究结果。

该研究小组评估了丹麦94个城市中年龄和性别调整后的痴呆发病率和社区社会经济地位(nSES)之间的关系。财富被分成收入四分位数,其他nSES变量根据中位数被分成高与低。

人口密度高(比值比[OR] 1.21, 95%置信区间[CI] 1.18-1.24)、高收入四分位数居民比例高(P<0001)、高教育水平(OR 1.19, 95% CI 1.15-1.22)与痴呆症发病率较高相关

丹麦94个城市的痴呆症发病率比率和95%置信区间

65岁以上居民比例高与年龄调整痴呆发病率低相关(OR 0.86, 95% CI 0.84 0.89)

nSES水平低的城市痴呆症诊断的年龄调整发病率较低。这些发现证实了之前的担忧,即在社会经济地位低的城市可能存在大量的痴呆症漏诊。

Ellen Holm等认为社会经济地位低的城市的患者比社会经济地位高的城市的患者更不可能被诊断,低nSES与诊断时严重痴呆病例比例高的相关关系证明了这一点。

原文出处

Frequency of missed or delayed diagnosis in dementia is associated with neighborhood socioeconomic status. Ellen Holm,Katja Kemp Jacobsen. 24 March 2022. https://doi.org/10.1002/trc2.12271

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    2022-04-28 Boyinsh
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    2022-06-13 zhouqu_8
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  5. 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  6. 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  7. 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2022, time=2022-03-25, status=1, ipAttribution=)]
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2022, time=2022-03-25, status=1, ipAttribution=)]
    2022-03-25 neuro.Dr

    老年性痴呆,未来还是希望借助神经电生理吧,也许更为有效!

    0

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