Diabetes Care:中青年糖尿病患者接种乙肝疫苗具有适度成本效益

2012-09-05 高晓方 医学论坛网

  美国学者的一项研究表明,20~59岁糖尿病患者接种乙肝疫苗具有适度成本效益,老年人群接种则不具备成本效益。论文于2012年8月28日在线发表于《糖尿病护理》(Diabetes Care)杂志。   研究者利用成本效益仿真模型对糖尿病患者(20~59岁)接种乙肝疫苗的成本效益进行分析;模拟受试者既往未接种疫苗或感染乙肝病毒。利用模型对急性和慢性乙肝病毒感染、并发症、质量调整生命年(Q

  美国学者的一项研究表明,20~59岁糖尿病患者接种乙肝疫苗具有适度成本效益,老年人群接种则不具备成本效益。论文于2012年8月28日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  研究者利用成本效益仿真模型对糖尿病患者(20~59岁)接种乙肝疫苗的成本效益进行分析;模拟受试者既往未接种疫苗或感染乙肝病毒。利用模型对急性和慢性乙肝病毒感染、并发症、质量调整生命年(QALY)和增量成本效益比进行评估。

  研究将接种528047例受试者,并预防4271例急性和256例慢性乙肝病毒感染。净医疗保健费用将增加9.14千万美元,QALY为1218;产生的成本效益比为75094美元/QALY。结果对年龄、折现率、糖尿病人群乙肝发病率和乙肝感染率最为敏感。成本效益比随接种年龄增加而升高。

  链接:

Hoerger TJ, Schillie S, Wittenborn JS, Bradley CL, Zhou F, Byrd K, Murphy TV.Cost-Effectiveness of Hepatitis B Vaccination in Adults With Diagnosed Diabetes.Diabetes Care. 2012 Aug 28


    

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    2012-09-07 xuyu

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