胶质母细胞瘤-话题@MedSci

#胶质母细胞瘤#

18篇内容 | 2247人围观

关注话题

话题活跃用户

#插入话题

插入图片

最新最热

[GetTopicListResponse(id=2199572, encodeId=d0cd21995e29d, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=697e4980403' target=_blank style='color:#2F92EE;'>#异柠檬酸脱氢酶#</a> <a href='/topic/show?id=380a11358e7b' target=_blank style='color:#2F92EE;'>#Mo-TAM#</a>, objectTitle=Cancer Cell：陆军军医大学卞修武/时雨/平轶芳发现恶性胶质瘤内肿瘤相关巨噬细胞新亚群, objectType=article, longId=821301, objectId=70e8821301cb, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/doctor-writing-D3K6QME.jpg, objectUrl=/article/show_article.do?id=70e8821301cb, replyNumber=0, likeNumber=4, createdTime=2024-04-21, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=70e8821301cb, moduleTitle=Cancer Cell：陆军军医大学卞修武/时雨/平轶芳发现恶性胶质瘤内肿瘤相关巨噬细胞新亚群, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=70e8821301cb)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2197010, encodeId=7faf219e01035, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=4e2640e283' target=_blank style='color:#2F92EE;'>#CAR-T细胞#</a> <a href='/topic/show?id=4fe2104642bf' target=_blank style='color:#2F92EE;'>#侧脑室内注射#</a>, objectTitle=NEJM：新型CAR-T细胞CARv3-TEAM-E脑室内注射治疗胶质母细胞瘤，5天肿瘤快速消退, objectType=article, longId=820292, objectId=262b8202922d, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20240403/62cf46b1eb3a438a80866cf3f98f2368-WNVLSEVjgdwP.jpg, objectUrl=/article/show_article.do?id=262b8202922d, replyNumber=0, likeNumber=11, createdTime=2024-04-05, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=262b8202922d, moduleTitle=NEJM：新型CAR-T细胞CARv3-TEAM-E脑室内注射治疗胶质母细胞瘤，5天肿瘤快速消退, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=262b8202922d)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2195679, encodeId=36fe21956e965, content=<a href='/topic/show?id=4e2640e283' target=_blank style='color:#2F92EE;'>#CAR-T细胞#</a> <a href='/topic/show?id=361f112e1161' target=_blank style='color:#2F92EE;'>#内皮唾酸蛋白#</a> <a href='/topic/show?id=73c423e2572' target=_blank style='color:#2F92EE;'>#乳腺癌#</a> <a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>, objectTitle= CAR-T细胞疗法研究进展（第42期）, objectType=article, longId=818072, objectId=c10c8180e203, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240323/1711182637709_2185383.png, objectUrl=/article/show_article.do?id=c10c8180e203, replyNumber=0, likeNumber=8, createdTime=2024-03-27, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2195212, encodeId=4de42195212cf, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=37ea11264e47' target=_blank style='color:#2F92EE;'>#CAR-T 细胞疗法#</a> <a href='/topic/show?id=4c496569c8' target=_blank style='color:#2F92EE;'>#EGFR#</a> <a href='/topic/show?id=e61311190563' target=_blank style='color:#2F92EE;'>#IL13RΑ2#</a>, objectTitle=Nat Med：初步临床试验表明鞘内注射靶向EGFR和IL13Rα2的双靶点CAR-T细胞有望治疗复发性胶质母细胞瘤, objectType=article, longId=817822, objectId=f49281e82214, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240323/1711193821858_2185383.png, objectUrl=/article/show_article.do?id=f49281e82214, replyNumber=0, likeNumber=7, createdTime=2024-03-25, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2194896, encodeId=af0821948964b, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=efb21516996' target=_blank style='color:#2F92EE;'>#RBBP6#</a> <a href='/topic/show?id=013311260532' target=_blank style='color:#2F92EE;'>#CPSF3#</a>, objectTitle=Cell Discov：西湖大学谢琦等团队揭示胶质母细胞瘤干细胞的选择性聚腺苷化, objectType=article, longId=817781, objectId=2c7081e7819f, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/doctor-working-in-a-hospital-PSQT2U3.jpg, objectUrl=/article/show_article.do?id=2c7081e7819f, replyNumber=0, likeNumber=13, createdTime=2024-03-23, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=2c7081e7819f, moduleTitle=Cell Discov：西湖大学谢琦等团队揭示胶质母细胞瘤干细胞的选择性聚腺苷化, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=2c7081e7819f)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2194997, encodeId=6b35219499e77, content=<a href='/topic/show?id=4a661126381b' target=_blank style='color:#2F92EE;'>#CAR-T细胞疗#</a> <a href='/topic/show?id=e61311190563' target=_blank style='color:#2F92EE;'>#IL13RΑ2#</a> <a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>, objectTitle=Nat Med：1期临床试验表明靶向IL13Rα2的CAR-T细胞有望治疗复发性高级别胶质瘤, objectType=article, longId=817821, objectId=5d0081e821af, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240323/1711191260338_2185383.png, objectUrl=/article/show_article.do?id=5d0081e821af, replyNumber=0, likeNumber=8, createdTime=2024-03-24, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2194636, encodeId=d9342194636f9, content=<a href='/topic/show?id=2acd40e7ba' target=_blank style='color:#2F92EE;'>#Car-T细胞疗法#</a> <a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=6a1c60356fb' target=_blank style='color:#2F92EE;'>#替莫唑胺#</a>, objectTitle=NEJM：1期临床试验表明下一代CAR-T细胞疗法有望治疗复发性胶质母细胞瘤, objectType=article, longId=817139, objectId=2ca481e139b1, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240315/1710457355364_2185383.png, objectUrl=/article/show_article.do?id=2ca481e139b1, replyNumber=0, likeNumber=7, createdTime=2024-03-22, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2190044, encodeId=6d11219004474, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=aa15e612333' target=_blank style='color:#2F92EE;'>#类器官#</a> <a href='/topic/show?id=5b1e651166d' target=_blank style='color:#2F92EE;'>#洛美他派#</a>, objectTitle=Nature子刊：利用人类干细胞培育出胶质母细胞瘤样类器官, objectType=article, longId=814486, objectId=70c0814486e3, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240223/1708692876674_2185383.png, objectUrl=/article/show_article.do?id=70c0814486e3, replyNumber=0, likeNumber=14, createdTime=2024-02-29, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2187974, encodeId=2144218e9749f, content=<a href='/topic/show?id=35c21222496' target=_blank style='color:#2F92EE;'>#mRNA#</a> <a href='/topic/show?id=107610211e67' target=_blank style='color:#2F92EE;'>#髓母细胞瘤#</a> <a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>, objectTitle=基因组医学| 脑肿瘤mRNA新产品和相关疫苗的开发和应用, objectType=article, longId=812008, objectId=1c638120088b, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/patient-meeting-a-doctor-PAYSRMZ.jpg, objectUrl=/article/show_article.do?id=1c638120088b, replyNumber=0, likeNumber=21, createdTime=2024-02-18, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=1c638120088b, moduleTitle=基因组医学| 脑肿瘤mRNA新产品和相关疫苗的开发和应用, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=1c638120088b)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2187952, encodeId=5e44218e95242, content=<a href='/topic/show?id=970e659640a' target=_blank style='color:#2F92EE;'>#淋巴瘤#</a> <a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>, objectTitle=European Radiology:原发性中枢神经系统淋巴瘤和胶质母细胞瘤的多参数MR分析, objectType=article, longId=813692, objectId=1aac81369263, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240217/1708181664067_1605392.png, objectUrl=/article/show_article.do?id=1aac81369263, replyNumber=0, likeNumber=27, createdTime=2024-02-18, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=1aac81369263, moduleTitle=European Radiology:原发性中枢神经系统淋巴瘤和胶质母细胞瘤的多参数MR分析, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=1aac81369263)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2185381, encodeId=eda12185381f1, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=9b93110e8539' target=_blank style='color:#2F92EE;'>#脑淋巴瘤#</a>, objectTitle=European Radiology：DSC-PWI序列在脑淋巴瘤和胶质母细胞瘤术前鉴别诊断中的应用, objectType=article, longId=811901, objectId=412281190195, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/202301012/1697153910219_4754896.jpeg, objectUrl=/article/show_article.do?id=412281190195, replyNumber=0, likeNumber=22, createdTime=2024-02-02, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=412281190195, moduleTitle=European Radiology：DSC-PWI序列在脑淋巴瘤和胶质母细胞瘤术前鉴别诊断中的应用, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=412281190195)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2183671, encodeId=b68921836e194, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=afc929130ad' target=_blank style='color:#2F92EE;'>#免疫细胞#</a> <a href='/topic/show?id=319b8e25637' target=_blank style='color:#2F92EE;'>#荧光染料#</a> <a href='/topic/show?id=63fb1104e1d0' target=_blank style='color:#2F92EE;'># Zman-seq#</a>, objectTitle=Cell：重大进展！首次开发出测量体内细胞随时间变化的方法, objectType=article, longId=810410, objectId=6a5f8104104c, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240121/1705836680096_2185383.png, objectUrl=/article/show_article.do?id=6a5f8104104c, replyNumber=0, likeNumber=17, createdTime=2024-01-24, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2183425, encodeId=b1d1218342546, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=7c802892e76' target=_blank style='color:#2F92EE;'>#克隆进化#</a> <a href='/topic/show?id=65c711043655' target=_blank style='color:#2F92EE;'>#微环境异质性#</a>, objectTitle=Cell：从三维全肿瘤角度揭示胶质母细胞瘤的进化和异质性, objectType=article, longId=810263, objectId=ca7981026357, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240120/1705745353049_2185383.png, objectUrl=/article/show_article.do?id=ca7981026357, replyNumber=0, likeNumber=25, createdTime=2024-01-23, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2181006, encodeId=ffa42181006bc, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=50a81e6869e' target=_blank style='color:#2F92EE;'>#TP53#</a> <a href='/topic/show?id=2fdf109886d5' target=_blank style='color:#2F92EE;'>#大脑类器官#</a>, objectTitle=Cell：首次利用人类胎儿脑组织培育出了大脑类器官, objectType=article, longId=808713, objectId=747b808e13f3, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20240110/1704842822493_2185383.png, objectUrl=/article/show_article.do?id=747b808e13f3, replyNumber=0, likeNumber=12, createdTime=2024-01-12, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2179675, encodeId=c76621e967517, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=63631096962d' target=_blank style='color:#2F92EE;'>#淋巴内皮样细胞#</a>, objectTitle=Nature Cancer：四川大学周圣涛等团队合作发现胶质母细胞瘤干细胞生长的调控新机制, objectType=article, longId=808488, objectId=0aa880848804, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/medical-staff-meeting-GXNVP9J.jpg, objectUrl=/article/show_article.do?id=0aa880848804, replyNumber=0, likeNumber=24, createdTime=2024-01-06, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=0aa880848804, moduleTitle=Nature Cancer：四川大学周圣涛等团队合作发现胶质母细胞瘤干细胞生长的调控新机制, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=0aa880848804)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2178331, encodeId=86e721e83310b, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=14112882177' target=_blank style='color:#2F92EE;'>#光热治疗#</a> <a href='/topic/show?id=6f38109468f3' target=_blank style='color:#2F92EE;'>#神经胶质细胞外泌体#</a>, objectTitle=中山大学邓文斌、邓冠军《AFM》：神经胶质细胞外泌体涂覆光热剂治疗恶性胶质瘤, objectType=article, longId=807590, objectId=760880e59050, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/medical-student-working-with-pad-on-the-PLC9ULE.jpg, objectUrl=/article/show_article.do?id=760880e59050, replyNumber=0, likeNumber=21, createdTime=2023-12-31, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=760880e59050, moduleTitle=中山大学邓文斌、邓冠军《AFM》：神经胶质细胞外泌体涂覆光热剂治疗恶性胶质瘤, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=760880e59050)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2177273, encodeId=e84821e7273bb, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=edd364149bc' target=_blank style='color:#2F92EE;'>#水凝胶#</a> <a href='/topic/show?id=040f10920e96' target=_blank style='color:#2F92EE;'>#腔内喷涂纳米调节剂#</a>, objectTitle=山东大学姜新义/陈晨/赵坤/张彩团队《AM》：腔内喷涂纳米调节剂包裹的水凝胶可用于术后胶质母细胞瘤免疫治疗, objectType=article, longId=806729, objectId=43f8806e29f5, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/conference-with-doctors-in-medical-aprons-PT29AAG.jpg, objectUrl=/article/show_article.do?id=43f8806e29f5, replyNumber=0, likeNumber=35, createdTime=2023-12-26, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=43f8806e29f5, moduleTitle=山东大学姜新义/陈晨/赵坤/张彩团队《AM》：腔内喷涂纳米调节剂包裹的水凝胶可用于术后胶质母细胞瘤免疫治疗, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=43f8806e29f5)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2173865, encodeId=96b521e3865ab, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a> <a href='/topic/show?id=57735e39801' target=_blank style='color:#2F92EE;'>#放射组学#</a>, objectTitle=Eur J Radiol：胶质母细胞瘤不同亚区的放射组学分割及分析, objectType=article, longId=804207, objectId=e01380420ee6, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/202301012/1697153910219_4754896.jpeg, objectUrl=/article/show_article.do?id=e01380420ee6, replyNumber=0, likeNumber=36, createdTime=2023-12-09, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=e01380420ee6, moduleTitle=Eur J Radiol：胶质母细胞瘤不同亚区的放射组学分割及分析, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=e01380420ee6)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2140482, encodeId=15412140482fc, content=<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>胶质母细胞瘤（GBM）是最常见和致命的脑肿瘤。由于这类肿瘤恶性程度极高、发展迅速，所以绝大部分患者预后极差：胶质母细胞瘤患者经过手术放化疗等治疗手段后，其生存中位数仅为15个月左右，五年生存率不到5%。, objectTitle=胶质母细胞瘤, objectType=topic, longId=84064, objectId=null, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=null, replyNumber=0, likeNumber=45, createdTime=2023-06-02, rootId=0, userName=yangchou, userId=88b489038, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2131311, encodeId=ec942131311a6, content=<a href='/topic/show?id=2ca46852d7' target=_blank style='color:#2F92EE;'>#Epacadostat#</a>+ <a href='/topic/show?id=4323140286a' target=_blank style='color:#2F92EE;'>#Pembrolizumab#</a>治疗晚期<a href='/topic/show?id=2493130e1a1' target=_blank style='color:#2F92EE;'>#NSCLC#</a>可使ORR和疾病控制率分别达到35%和63%；去年9月的ESMO2017大会上Incyte宣布I/II期ECHO-202（KEYNOTE-037）研究中epacadostat+ pembrolizumab可使晚期<a href='/topic/show?id=330410333110' target=_blank style='color:#2F92EE;'>#黑色素瘤#</a>患者的ORR达到56%；去年11月BMS公布的Opdivo联合自家<a href='/topic/show?id=9517942978' target=_blank style='color:#2F92EE;'>#IDO抑制剂#</a><a href='/topic/show?id=6cd310620285' target=_blank style='color:#2F92EE;'>#BMS-986205#</a>的I/II期研究中，<a href='/topic/show?id=843a85e9421' target=_blank style='color:#2F92EE;'>#膀胱癌#</a>和<a href='/topic/show?id=146246308d1' target=_blank style='color:#2F92EE;'>#宫颈癌#</a>队列患者也取得了积极结果。但三期失败，不过，最近文献来看，在<a href='/topic/show?id=01858406438' target=_blank style='color:#2F92EE;'>#胶质母细胞瘤#</a>可能<a href='/topic/show?id=2853942e78' target=_blank style='color:#2F92EE;'>#IDO1#</a>仍然有相当的潜力！！, objectTitle=ECHO-301意外失败：IDO抑制剂类肿瘤免疫抑制剂路在何方？, objectType=article, longId=134457, objectId=46d813445ec7, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/webeditor/uploadfile/201804/20180407094338753.JPEG, objectUrl=/article/show_article.do?id=46d813445ec7, replyNumber=0, likeNumber=81, createdTime=2023-05-10, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=46d813445ec7, moduleTitle=ECHO-301意外失败：IDO抑制剂类肿瘤免疫抑制剂路在何方？, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=46d813445ec7)], followStatus=false, userIsMember=true, type=1, lengthMark=1)] 梅斯话题小助手

胶质母细胞瘤

2020-05-29发表于威斯康星

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #异柠檬酸脱氢酶# #Mo-TAM#

Cancer Cell：陆军军医大学卞修武/时雨/平轶芳发现恶性胶质瘤内肿瘤相关巨噬细胞新亚群

2024-04-21发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #CAR-T细胞# #侧脑室内注射#

NEJM：新型CAR-T细胞CARv3-TEAM-E脑室内注射治疗胶质母细胞瘤，5天肿瘤快速消退

2024-04-05发表于威斯康星

梅斯管理员 (审核中...)

前往app查看评论内容

#CAR-T细胞# #内皮唾酸蛋白# #乳腺癌# #胶质母细胞瘤#

2024-03-27发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #CAR-T 细胞疗法# #EGFR# #IL13RΑ2#

2024-03-25发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #RBBP6# #CPSF3#

Cell Discov：西湖大学谢琦等团队揭示胶质母细胞瘤干细胞的选择性聚腺苷化

2024-03-23发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#CAR-T细胞疗# #IL13RΑ2# #胶质母细胞瘤#

2024-03-24发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#Car-T细胞疗法# #胶质母细胞瘤# #替莫唑胺#

2024-03-22发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #类器官# #洛美他派#

2024-02-29发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#mRNA# #髓母细胞瘤# #胶质母细胞瘤#

基因组医学| 脑肿瘤mRNA新产品和相关疫苗的开发和应用

2024-02-18发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#淋巴瘤# #胶质母细胞瘤#

European Radiology:原发性中枢神经系统淋巴瘤和胶质母细胞瘤的多参数MR分析

2024-02-18发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #脑淋巴瘤#

European Radiology：DSC-PWI序列在脑淋巴瘤和胶质母细胞瘤术前鉴别诊断中的应用

2024-02-02发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #免疫细胞# #荧光染料# # Zman-seq#

2024-01-24发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #克隆进化# #微环境异质性#

2024-01-23发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #TP53# #大脑类器官#

2024-01-12发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #淋巴内皮样细胞#

Nature Cancer：四川大学周圣涛等团队合作发现胶质母细胞瘤干细胞生长的调控新机制

2024-01-06发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #光热治疗# #神经胶质细胞外泌体#

中山大学邓文斌、邓冠军《AFM》：神经胶质细胞外泌体涂覆光热剂治疗恶性胶质瘤

2023-12-31发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #水凝胶# #腔内喷涂纳米调节剂#

山东大学姜新义/陈晨/赵坤/张彩团队《AM》：腔内喷涂纳米调节剂包裹的水凝胶可用于术后胶质母细胞瘤免疫治疗

2023-12-26发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#胶质母细胞瘤# #放射组学#

Eur J Radiol：胶质母细胞瘤不同亚区的放射组学分割及分析

2023-12-09发表于上海

yangchou (审核中...)

前往app查看评论内容

#胶质母细胞瘤#胶质母细胞瘤（GBM）是最常见和致命的脑肿瘤。由于这类肿瘤恶性程度极高、发展迅速，所以绝大部分患者预后极差：胶质母细胞瘤患者经过手术放化疗等治疗手段后，其生存中位数仅为15个月左右，五年生存率不到5%。

2023-06-02

(审核中...)

前往app查看评论内容

全文收起 #Epacadostat#+ #Pembrolizumab#治疗晚期#NSCLC#可使ORR和疾病控制率分别达到35%和63%；去年9月的ESMO2017大会上Incyte宣布I/II期ECHO-202（KEYNOTE-037）研究中epacadostat+ pembrolizumab可使晚期#黑色素瘤#患者的ORR达到56%；去年11月BMS公布的Opdivo联合自家#IDO抑制剂##BMS-986205#的I/II期研究中，#膀胱癌#和#宫颈癌#队列患者也取得了积极结果。但三期失败，不过，最近文献来看，在#胶质母细胞瘤#可能#IDO1#仍然有相当的潜力！！

ECHO-301意外失败：IDO抑制剂类肿瘤免疫抑制剂路在何方？

2023-05-10发表于上海

科室
- - 订阅+
  - 更多科室
工具
服务