J Cosmet Dermatol:多模态CO2和1570 nm激光治疗面部萎缩性痤疮瘢痕

2024-04-22 MedSci原创 MedSci原创 发表于上海

多模态CO2和1570 nm激光治疗可改善面部萎缩性痤疮瘢痕。

瘢痕是寻常痤疮最常见的长期并发症之一,可造成相当大的美容、心理和社会负担,并对患者生活质量产生负面影响其治疗方式复杂多样。最近上市的自动混合点阵激光系统集成了可调谐的CO21570 nm激光,可单独、同时或序贯操作。

J Cosmet Dermatol最新的一篇研究报告,研究者评估了序贯多模态剥脱10600 nm和非剥脱1570 nm激光治疗对痤疮瘢痕的影响。

20 ~ 50岁、Fitzpatrick皮肤II~IV型、无活动性痤疮、寻求改善痤疮瘢痕外观的成年患者被纳入研究。每例患者间隔2个月接受3次多模态激光治疗。治疗前,治疗区域进行彻底清洗和消毒,治疗使用ProScan Hybrid applicator (Alma Laser Ltd, Caesarea, Israel) CO2激光 (45 W, 1 ms)和1570 nm激光(10 W, 3 ms)。在整个治疗过程中,使用外部空气冷却装置(Cryo 6, Zimmer Aesthetics , Germany)对皮肤进行冷却。未使用表面麻醉药。此外,受试者每天至少涂3次修复霜,在阳光下每2小时涂一次防晒系数50+的防晒霜。在基线和最后一次治疗后6个月评估瘢痕体积和受累面积。采用标准5Likert量表进行患者满意度评分。

16例患者进行剥脱联合点阵非剥脱激光治疗痤疮瘢痕。男性9例,女性7例,平均年龄29.3±7.9岁。Fitzpatrick皮肤分型:III型11例(68.8%),II型4例(25%),IV型1例。基线时,所有患者均有箱车型和滚轮型瘢痕,仅3例患者有冰锥型瘢痕。治疗后6个月,平均瘢痕体积从基线时的5.7±5.2 mm3改善至3.1±3.0 mm3,平均受累面积从165.6±134.0mm2改善至94.0±80.1mm2,分别较基线减少47.0±7.9%和43.2±8.6%。患者对治疗效果满意度高,治疗过程中及随访期间均未发生严重不良反应。

综上,多模态CO21570 nm激光治疗可改善面部萎缩性痤疮瘢痕。根据美容区域、瘢痕特征和皮肤光型定制治疗间隔和激光参数可能进一步提高治疗效果,并扩大其对其他皮肤问题的适用范围。

原始出处:

García PN, Andrino RL.  Resurfacing  of atrophic facial acne scars with a multimodality CO2 and 1570 nm laser system.  J Cosmet Dermatol.  2024;23(Suppl.  1):13-18.  doi:10.1111/jocd.16283

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[AttachmentFileName(sort=1, fileName=J of Cosmetic Dermatology - 2024 - García - Resurfacing of atrophic facial acne scars with a multimodality CO2 and 1570 nm.pdf)] GetArticleByIdResponse(id=68b28226601c, projectId=1, sourceId=null, title=J Cosmet Dermatol:多模态CO2和1570 nm激光治疗面部萎缩性痤疮瘢痕, articleFrom=MedSci原创, journalId=11903, copyright=原创, creationTypeList=[1], summary=多模态CO2和1570 nm激光治疗可改善面部萎缩性痤疮瘢痕。, cover=https://img.medsci.cn/20221109/1668017370503_4754896.png, authorId=0, author=, originalUrl=, linkOutUrl=, content=<p><span style="color: #212121;">瘢痕是寻常痤疮最常见的长期并发症之一,</span><span style="color: #212121;">可造成相当大的美容、心理和社会负担,并对患者<a href="https://m.medsci.cn/scale/show.do?id=4c862426ef">生活质量</a>产生负面影响</span><span style="color: #212121;">。</span><span style="color: #212121;">其治疗方式复杂多样。最近上市的自动混合点阵激光系统集成了可调谐的</span><span style="color: #212121;">CO2</span><span style="color: #212121;">和</span><span style="color: #212121;">1570 nm</span><span style="color: #212121;">激光,可单独、同时或</span><span style="color: #212121;">序贯</span><span style="color: #212121;">操作。</span></p> <p><span style="color: #212121;">J Cosmet Dermatol</span><span style="color: #3b3030;">最新的一篇研究报告,</span>研究者<span style="color: #212121;">评估了序贯</span><span style="color: #212121;">多模态剥脱</span><span style="color: #212121;">10600 nm</span><span style="color: #212121;">和非剥脱</span><span style="color: #212121;">1570 nm</span><span style="color: #212121;">激光</span><span style="color: #212121;">治疗对痤疮瘢痕的影响。</span></p> <p><span style="color: #212121;"> <img class="wscnph" src="https://img.medsci.cn/20240421/1713705395842_8439950.jpg" /></span></p> <p><span style="color: #212121;">20 ~ 50</span><span style="color: #212121;">岁、</span><span style="color: #212121;">Fitzpatrick</span><span style="color: #212121;">皮肤</span><span style="color: #212121;">II~IV</span><span style="color: #212121;">型、无活动性痤疮、寻求改善痤疮瘢痕外观的成年患者被纳入研究。每例患者间隔</span><span style="color: #212121;">2</span><span style="color: #212121;">个月接受</span><span style="color: #212121;">3</span><span style="color: #212121;">次多模态激光治疗。治疗前,</span><span style="color: #212121;">治疗区域进行彻底清洗和消毒,治疗使用ProScan Hybrid applicator (Alma Laser Ltd, Caesarea, Israel) CO2激光 (45 W, 1 ms)和1570 nm激光(10 W, 3 ms)。在整个治疗过程中,使用外部空气冷却装置(Cryo 6, Zimmer Aesthetics</span> <span style="color: #212121;">, Germany)</span><span style="color: #212121;">对皮肤进行冷却。未使用表面麻醉药。此外,受试者每天至少涂3次修复霜,在阳光下每2小时涂一次防晒系数50+的防晒霜。</span><span style="color: #212121;">在基线和最后一次治疗后</span><span style="color: #212121;">6</span><span style="color: #212121;">个月评估瘢痕体积和受累面积。采用标准</span><span style="color: #212121;">5</span><span style="color: #212121;">分</span><span style="color: #212121;">Likert</span><span style="color: #212121;">量表进行患者满意度评分。</span></p> <p>16例患者进行剥脱联合点阵非剥脱激光治疗痤疮瘢痕。男性9例,女性7例,平均年龄29.3&plusmn;7.9岁。Fitzpatrick皮肤分型:III型11例(68.8%),II型4例(25%),IV型1例。基线时,所有患者均有箱车型和滚轮型瘢痕,仅3例患者有冰锥型瘢痕。治疗后6个月,平均瘢痕体积从基线时的5.7&plusmn;5.2 mm3改善至3.1&plusmn;3.0 mm3,平均受累面积从165.6&plusmn;134.0mm2改善至94.0&plusmn;80.1mm2,分别较基线减少47.0&plusmn;7.9%和43.2&plusmn;8.6%。患者对治疗效果满意度高,治疗过程中及随访期间均未发生严重不良反应。</p> <p><img class="wscnph" src="https://img.medsci.cn/20240421/1713705405430_8439950.jpg" /><img class="wscnph" src="https://img.medsci.cn/20240421/1713705410300_8439950.jpg" /></p> <p>综上,多模态CO2<span style="color: #2a2b2e;">和</span>1570 nm激光治疗可改善面部萎缩性痤疮瘢痕。根据美容区域、瘢痕特征和皮肤光型定制治疗间隔和激光参数可能进一步提高治疗效果,并扩大其对其他皮肤问题的适用范围。</p> <p><span style="color: #808080; font-size: 12px;">原始出处:</span></p> <p><span style="color: #808080; font-size: 12px;">Garc&iacute;a PN, Andrino RL.&nbsp; Resurfacing&nbsp; of atrophic facial acne scars with a multimodality CO2 and 1570&thinsp;nm laser system.&nbsp; J Cosmet Dermatol.&nbsp; 2024;23(Suppl.&nbsp; 1):13-18.&nbsp; doi:10.1111/jocd.16283</span></p>, belongTo=, tagList=[TagDto(tagId=25497, tagName=激光治疗), TagDto(tagId=123642, tagName=痤疮瘢痕)], categoryList=[CategoryDto(categoryId=28, categoryName=整形美容, tenant=100), CategoryDto(categoryId=39, categoryName=皮肤性病, tenant=100), CategoryDto(categoryId=84, categoryName=研究进展, tenant=100), CategoryDto(categoryId=20656, categoryName=梅斯医学, tenant=100)], articleKeywordId=0, articleKeyword=, articleKeywordNum=6, guiderKeywordId=0, guiderKeyword=, guiderKeywordNum=6, opened=1, paymentType=1, paymentAmount=0, recommend=0, recommendEndTime=null, sticky=0, stickyEndTime=null, allHits=766, appHits=8, showAppHits=0, pcHits=12, showPcHits=758, likes=0, shares=3, comments=3, approvalStatus=1, publishedTime=Mon Apr 22 11:06:00 CST 2024, publishedTimeString=2024-04-22, pcVisible=1, appVisible=1, editorId=6556111, editor=整形科新前沿, waterMark=0, formatted=0, deleted=0, version=3, createdBy=d3b78439950, createdName=布兜小吴, createdTime=Sun Apr 21 21:18:06 CST 2024, updatedBy=92910, updatedName=rayms, updatedTime=Mon Apr 22 11:17:04 CST 2024, ipAttribution=上海, attachmentFileNameList=[AttachmentFileName(sort=1, fileName=J of Cosmetic Dermatology - 2024 - García - Resurfacing of atrophic facial acne scars with a multimodality CO2 and 1570 nm.pdf)])
J of Cosmetic Dermatology - 2024 - García - Resurfacing of atrophic facial acne scars with a multimodality CO2 and 1570 nm.pdf
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    2024-04-22 屋顶瞄爱赏月 来自贵州省

    签到学习

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    2024-04-22 1dea4a7em68(暂无匿称) 来自福建省

    谢谢分享

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    2024-04-22 1209e435m98(暂无昵称) 来自浙江省

    学习了,谢谢分享

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低水平激光治疗(LLLT)又称光生物调控治疗(PBMT),可以降低头颈部癌症患者接受化学放疗的口腔黏膜炎(OM)的发生率和严重程度,但目前还缺少有关疗效和安全性的随机数据,治疗剂量为4J/cm2。

不同形状和深浅的凹陷性痤疮瘢痕,用激光怎么治疗?

箱车型的痤疮瘢痕有一个呈“U”形,比冰锥样瘢痕更加宽大,有较多的组织缺损。箱车型的瘢痕很少有底部红斑,表现为成熟的萎缩性瘢痕,且边缘锐利,有明显的阶梯感。

【热点指南分享】激光治疗设备同品种临床评价注册审查指导原则

为进一步规范激光治疗设备医疗器械的管理,国家药监局器审中心组织制定了《激光治疗设备同品种临床评价注册审查指导原则》,现予发布。

一文了解激光在痤疮治疗中的应用

寻常痤疮是一种常见的毛囊性疾病,其发病机制是多因素的,包括毛囊过度角化、激素相关的过度皮脂生成等。本文整理了一些激光治疗痤疮的相关研究供大家学习。

颧部褐青色痣的激光治疗进展

随着人们生活水平的提高,光电技术的发展,激光治疗逐渐成为颧部褐青色痣治疗的首选。

J Clin Med:低水平激光治疗对多年过敏性鼻炎患者的临床疗效和安全性

过敏性鼻炎(AR)是一种常见的疾病,会影响日常活动,降低生活质量。传统的治疗方法往往不能完全治愈症状,且已经尝试了许多新的治疗模式。

Am J Clin Dermatol:早期治疗可改善太田痣的预后

太田痣是一种面部色素沉着胎记,激光治疗目前是一线治疗,但何时开始治疗还没有制定指导方针,本文的目的是确定接受激光治疗太田痣的患者的疗效和安全性、复发风险和开始治疗年龄之间的相关性。

罕见并发症:黄金微针术后迟发性不良反应三例

今天分享的罕见并发症来自@周展超等医生。

Skin Res Technol:595 nm脉冲染料激光治疗手足病毒性疣的临床证据

使用波长为595 nm的脉冲染料激光治疗被证明是一种可耐受的和安全的治疗病毒疣的方法。

J Cosmet Dermatol:强脉冲光用于治疗血管性和色素性病变

新型强脉冲光治疗对血管性和色素性皮损有较好的疗效。